Chakravarti A, Bhargava R, Bhattacharya S
Department of Otorhinolaryngology, Lady Hardinge Medical College and Kalawati Saran Children Hospital, Shahid Bhagat Singh Marg, New Delhi, India.
Int J Pediatr Otorhinolaryngol. 2013 May;77(5):869-72. doi: 10.1016/j.ijporl.2013.02.025. Epub 2013 Mar 23.
Mucormycosis is an acute fulminant fungal infection with characteristic early angioinvasion. High index of suspicion is crucial for the diagnosis, as prompt and appropriate management can considerably reduce morbidity and mortality. Primary cutaneous mucormycosis occurs mostly in adults and is rare in the pediatric age group, most often noted in immunocompromised children. In this series we present three cases of cutaneous mucormycosis of the nose, among which one was immunocompetent and rest were immunocompromised. All three were successfully treated with local debridement and amphotericin B.
毛霉病是一种急性暴发性真菌感染，具有特征性的早期血管侵袭性。高度的怀疑指数对诊断至关重要，因为及时且恰当的治疗可显著降低发病率和死亡率。原发性皮肤毛霉病大多发生于成人，在儿童年龄组中罕见，最常见于免疫功能低下的儿童。在本系列中，我们报告了3例鼻部皮肤毛霉病病例，其中1例免疫功能正常，其余为免疫功能低下者。所有3例均通过局部清创术和两性霉素B成功治愈。
