Cristescu C, Velişcu Andreea, Marinescu B, Pătraşcu Anca, Traşcă E T, Pop O T
“Prof. Dr. Panait Sârbu” Clinical Hospital of Obstetrics and Gynecology, Bucharest, Romania.
Rom J Morphol Embryol. 2013;54(1):91-7.
Endometriosis is a benign disease defined by the presence of endometrial glands and stroma outside of the uterus and is associated with both pelvic pain and infertility. The most common sites of endometriosis, in decreasing order of frequency, are the ovaries, anterior and posterior cul-de-sac, posterior broad ligaments, uterosacral ligaments, uterus, fallopian tubes, sigmoid colon, appendix, and round ligaments. The main treatment is surgical, but often-microscopic islands of endometrial tissue remain, which proliferate and are responsible for relapses. We tested the efficacy of two drugs (Medroxyprogesterone and Triptorelinum), administered for six months to prevent recurrence after surgery. Treatment with Medroxyprogesterone was 100% effective in terms of relapse, while Triptorelinum could not prevent recurrence of endometriosis.
子宫内膜异位症是一种良性疾病，其定义为子宫外存在子宫内膜腺体和间质，并与盆腔疼痛和不孕相关。子宫内膜异位症最常见的部位，按发生频率从高到低依次为卵巢、前后陷凹、阔韧带后叶、子宫骶韧带、子宫、输卵管、乙状结肠、阑尾和圆韧带。主要治疗方法是手术，但通常会残留微小的子宫内膜组织岛，这些组织会增殖并导致复发。我们测试了两种药物（甲羟孕酮和曲普瑞林）的疗效，这两种药物给药六个月以预防术后复发。就复发而言，甲羟孕酮治疗的有效率为100%，而曲普瑞林不能预防子宫内膜异位症的复发。
