Fernandes V P I, Lima M C L, Camargo E E, Collares E F, Bustorff-Silva J M, Lomazi E A
Gastroenterologia Pediátrica, Departamento de Pediatria, Universidade Estadual de Campinas, Campinas, SP, Brasil.
Braz J Med Biol Res. 2013 Mar;46(3):293-8. doi: 10.1590/1414-431x20132448. Epub 2013 Mar 15.
The objective of this study was to evaluate gastric emptying (GE) in pediatric patients with functional constipation. GE delay has been reported in adults with functional constipation. Gastric emptying studies were performed in 22 children with chronic constipation, fecal retention and fecal incontinence, while presenting fecal retention and after resuming regular bowel movements. Patients (18 boys, median age: 10 years; range: 7.2 to 12.7 years) were evaluated in a tertiary pediatric gastroenterology clinic. Gastric half-emptying time of water (reference range: 12 ± 3 min) was measured using a radionuclide technique immediately after first patient evaluation, when they presented fecal impaction (GE1), and when they achieved regular bowel movements (GE2), 12 ± 5 weeks after GE1. At study admission, 21 patients had reported dyspeptic symptoms, which were completely relieved after resuming regular bowel movements. Medians (and interquartile ranges) for GE1 and GE2 were not significantly different [27.0 (16) and 27.5 (21) min, respectively (P = 0.10)]. Delayed GE seems to be a common feature among children with chronic constipation and fecal retention. Resuming satisfactory bowel function and improvement in dyspeptic symptoms did not result in normalization of GE data.
本研究的目的是评估功能性便秘小儿患者的胃排空情况。已有报道称成人功能性便秘患者存在胃排空延迟。对22例患有慢性便秘、粪便潴留和大便失禁的儿童进行了胃排空研究，研究时间为出现粪便潴留时以及恢复正常排便后。患者（18名男孩，中位年龄：10岁；范围：7.2至12.7岁）在一家三级儿科胃肠病诊所接受评估。在首次评估患者后，即当他们出现粪便嵌塞时（GE1），以及在GE1后12±5周恢复正常排便时（GE2），使用放射性核素技术测量水的胃半排空时间（参考范围：12±3分钟）。在研究入院时，21例患者报告有消化不良症状，恢复正常排便后这些症状完全缓解。GE1和GE2的中位数（及四分位间距）无显著差异[分别为27.0（16）和27.5（21）分钟（P = 0.10）]。胃排空延迟似乎是慢性便秘和粪便潴留儿童的一个常见特征。恢复满意的肠道功能和消化不良症状改善并未使胃排空数据恢复正常。
