同步发生的肺支气管相关淋巴组织淋巴瘤与肺鳞状细胞癌：巧合还是存在关联？

Synchronous BALT Lymphoma and Squamous Cell Carcinoma of the Lung: Coincidence or Linkage?

作者信息

Oikonomou Anastasia, Astrinakis Emanuelle, Kotsianidis Ioannis, Kaloutsi Vassiliki, Didilis Vassileios, Tsatalas Konstantinos, Prassopoulos Panos

机构信息

Department of Radiology, University Hospital of Alexandroupolis, Democritus University of Thrace, Dragana, 68100 Alexandroupolis, Greece.

出版信息

Case Rep Oncol Med. 2013;2013:420393. doi: 10.1155/2013/420393. Epub 2013 Feb 28.

DOI:10.1155/2013/420393

PMID:23533872

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3600273/

Abstract

A 72-year-old man presented with weight loss, fever, and malaise. Chest radiograph and CT revealed two large ill-defined masses in middle and left lower lobes. CT-guided biopsy of left lower lobe mass disclosed bronchus-associated lymphoid tissue (BALT) lymphoma. Middle lobe mass was considered second deposit in contralateral lung. The patient received chemotherapy for BALT. Followup CT disclosed regression of left lower lobe mass and stability of middle-lobe mass and of right paratracheal lymph nodes. CT-guided biopsy of middle-lobe mass revealed squamous cell lung carcinoma. Surgical biopsy of right paratracheal lymph nodes revealed malignancy. Disease was staged T3, N2, and M0. Combined chemotherapy for lung cancer and BALT lymphoma was initiated.

摘要

一名72岁男性出现体重减轻、发热和全身乏力症状。胸部X光片和CT显示中肺叶和左下肺叶有两个边界不清的大肿块。对左下肺叶肿块进行CT引导下活检，结果显示为支气管相关淋巴组织（BALT）淋巴瘤。中肺叶肿块被认为是对侧肺的继发性病灶。该患者接受了针对BALT的化疗。随访CT显示左下肺叶肿块缩小，中肺叶肿块及右气管旁淋巴结稳定。对中肺叶肿块进行CT引导下活检，结果显示为肺鳞状细胞癌。对右气管旁淋巴结进行手术活检显示为恶性肿瘤。疾病分期为T3、N2和M0。遂开始针对肺癌和BALT淋巴瘤的联合化疗。