Schaffer-Kronberger E, Eber B, Wawschinek O, Dusleag J, Friehs I, Gogg R, Petek W, Klein W
Abteilung für Kardiologie, Medizinischen Universitätsklinik Graz.
Acta Med Austriaca. 1990;17(1):22-4.
The trace element selenium plays an important role in the oxidation of lipids and is therefore closely associated with atherosclerosis. In a series of 49 unselected male patients having undergone coronary angiography, the serum selenium level was determined using flameless atomic absorption spectrometry (Zeeman technique), and compared to a standard (Seronorm; Nycomed). In the whole series the serum selenium levels were markedly decreased with no significant difference between patients with or without coronary artery disease. The severity of the coronary artery disease (CAD) did not correlate with the selenium level. However, patients with prior myocardial infarction had a significant higher selenium level than those without. Thus, the level of selenium does not appear to be a marker or a risk factor for coronary artery disease.
微量元素硒在脂质氧化过程中起重要作用，因此与动脉粥样硬化密切相关。在一组49例未经挑选且已接受冠状动脉造影的男性患者中，采用无火焰原子吸收光谱法（塞曼技术）测定血清硒水平，并与标准值（Seronorm；Nycomed）进行比较。在整个系列中，血清硒水平显著降低，患冠状动脉疾病和未患冠状动脉疾病的患者之间无显著差异。冠状动脉疾病（CAD）的严重程度与硒水平无关。然而，既往有心肌梗死的患者的硒水平显著高于无心肌梗死的患者。因此，硒水平似乎不是冠状动脉疾病的标志物或危险因素。
