Conboy Gary, Stewart Tonya, O'Brien Susan
Department of Pathology and Microbiology, Atlantic Veterinary College, Charlottetown, PEI, Canada.
J Am Anim Hosp Assoc. 2013 May-Jun;49(3):204-9. doi: 10.5326/JAAHA-MS-5832. Epub 2013 Mar 27.
Numerous bipolar plugged capillarid eggs were detected on a routine centrifugal fecal flotation examination of a 2 yr old castrated male boxer-Chinese shar pei mixed-breed. The eggs were identified as Eucoleus boehmi (E. boehmi), the nasal capillarid, based on size and shell wall surface morphology. The dog had a history of chronic sneezing (> 5 times/day) and intermittent postexercise nasal discharge. Currently, there are no anthelmintics approved for use in dogs for the treatment of E. boehmi. Treatment of the dog with 0.5-1 mg/kg milbemycin oxime was ineffective, but treatment with 2 mg/kg milbemycin oxime resulted in negative fecal examinations 7-28 days and 5 mo posttreatment. The dog's postexertion nasal discharge greatly lessened, and the sneezing behavior improved (it was only noted 2-3 times/wk), but neither the discharge nor sneezing completely resolved following the anthelmintic treatments. Use of milbemycin oxime at an increased dose (2 mg/kg) appeared to be an effective treatment against E. boehmi infection in this dog based on clinical response and the cessation of fecal egg shedding.
在对一只2岁去势的雄性拳师犬与中国沙皮犬的混种犬进行常规粪便离心漂浮检查时,发现了大量双极插头状毛细线虫卵。根据虫卵大小和壳壁表面形态,这些虫卵被鉴定为鼻毛细线虫(Eucoleus boehmi,E. boehmi)。该犬有慢性打喷嚏(每天>5次)和运动后间歇性鼻分泌物增多的病史。目前,尚无被批准用于犬治疗鼻毛细线虫的驱虫药。用0.5 - 1毫克/千克的米尔贝霉素肟治疗该犬无效,但用2毫克/千克的米尔贝霉素肟治疗后,在治疗后7 - 28天和5个月时粪便检查呈阴性。该犬运动后的鼻分泌物明显减少,打喷嚏行为有所改善(每周仅出现2 - 3次),但驱虫治疗后鼻分泌物和打喷嚏症状均未完全消失。基于临床反应和粪便虫卵停止排出,使用增加剂量(2毫克/千克)的米尔贝霉素肟似乎是治疗该犬鼻毛细线虫感染的有效方法。