Bonadei Ivano, Vizzardi Enrico, D'Aloia Antonio, Quinzani Filippo, Magatelli Marco, Salghetti Francesca, Curnis Antonio, Metra Marco
Recenti Prog Med. 2013 Feb;104(2):76-9. doi: 10.1701/1241.13710.
Currently, cardiac resynchronization therapy (CRT) is a treatment for heart failure refractory to optimized medical therapy. However, approximately 30% -45% of patients selected according to the guidelines, are "non responders" to CRT. Since the CRT is an invasive treatment, the candidates for such therapy should be carefully selected to ensure an optimal clinical benefit and instrumental. Despite its demonstrated effectiveness in reducing mortality and hospitalizations in patients with chronic heart failure on optimal medical therapy, the diagnosis of dyssynchrony is not easy. On the one hand, some echocardiographic indices have proved unreliable, other, more complex parameters still need to be validated before being implemented in clinical routine. The purpose of our paper is to evaluate echocardiographic techniques and not consolidated in patient response to CRT.
目前,心脏再同步治疗(CRT)是一种用于治疗经优化药物治疗后仍难治的心力衰竭的方法。然而,根据指南选择的患者中,约30% - 45%对CRT“无反应”。由于CRT是一种侵入性治疗,应仔细选择此类治疗的候选者,以确保获得最佳的临床益处和器械效果。尽管已证明其在优化药物治疗的慢性心力衰竭患者中可有效降低死亡率和住院率,但不同步的诊断并不容易。一方面,一些超声心动图指标已被证明不可靠,另一方面,其他更复杂的参数在临床常规应用之前仍需验证。我们论文的目的是评估超声心动图技术以及未在患者对CRT的反应中得到巩固的情况。