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[一例膀胱癌合并双侧输尿管原位癌]

[A case of bladder cancer with bilateral ureteral carcinoma in situ].

作者信息

Ishibashi Y, Sakai N, Fukuoka H, Sakanishi S

机构信息

Department of Urology, Yokohama Minami Kyosai Hospital.

出版信息

Hinyokika Kiyo. 1990 Mar;36(3):333-6.

PMID:2353606
Abstract

A case of bladder cancer with bilateral ureteral carcinoma in situ (CIS) is presented. A 55-year-old male had gross hematuria and urinary retention. Cystoscopy revealed diffuse broad-based papillary tumors, which proved to be transitional cell carcinoma (G2) with CIS and submucosal invasion microscopically. Excretory urography showed normal upper urinary tracts except stasis of bilateral lower ureters. Neither lymph node swelling nor distant metastasis was found by computed tomography. Therefore the patient underwent total cystourethrectomy, pelvic lymph-adenectomy, and construction of an ileal conduit. Histological examination of the specimens demonstrated CIS on bilateral ureteral stumps on the renal side, which, however, was not continuous to that of the bladder. Much attention should be paid to upper urinary tracts for ureteral lesions before cystectomy in such bladder tumors and the proximal stump of the ureter should be examined using frozen section at the operation, but these were not sufficient in the present case in which skip lesions of the ureters were seen apart from the bladder.

摘要

本文报告一例膀胱癌合并双侧输尿管原位癌(CIS)的病例。一名55岁男性出现肉眼血尿和尿潴留。膀胱镜检查发现弥漫性广基乳头状肿瘤,显微镜检查证实为移行细胞癌(G2),伴有原位癌和黏膜下浸润。排泄性尿路造影显示除双侧下输尿管淤滞外,上尿路正常。计算机断层扫描未发现淋巴结肿大或远处转移。因此,患者接受了全膀胱尿道切除术、盆腔淋巴结清扫术和回肠代膀胱术。标本的组织学检查显示,双侧输尿管肾侧残端存在原位癌,但与膀胱的原位癌不连续。对于此类膀胱肿瘤,在膀胱切除术之前应高度关注上尿路的输尿管病变,术中应对输尿管近端残端进行冰冻切片检查,但在本病例中,输尿管出现了与膀胱不连续的跳跃性病变,上述措施并不充分。

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