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减重手术后长期反流相关症状:袖状胃切除术与腹腔镜可调节胃束带术的比较。

Long-term reflux-related symptoms after bariatric surgery: comparison of sleeve gastrectomy versus laparoscopic adjustable gastric banding.

机构信息

Digestive Diseases Institute, Shaare Zedek Medical Center, Jerusalem, Israel.

出版信息

Lung. 2013 Jun;191(3):289-93. doi: 10.1007/s00408-013-9454-8. Epub 2013 Mar 28.

Abstract

BACKGROUND

Long-term pulmonary reflux-related symptoms following laparoscopic adjustable gastric banding (LAGB) and laparoscopic sleeve gastrectomy (LSG) have not been reported.

METHODS

We designed a retrospective analysis of consecutive patients who underwent LAGB or LSG between January 2000 and December 2010. All patients provided detailed history and physical examination. We assessed both early and late reflux-related symptoms. All patients underwent spirometry and chest X-ray (CXR).

RESULTS

The analysis included 307 patients who underwent either LAGB (n = 193) or LSG (n = 114). Mean age was 43 ± 12 and 46 ± 11 years, respectively; 144 (76.6 %) and 83 (73 %) were female, respectively. Similar rates of previous pulmonary disease were noted in both LAGB and LSG groups (10.9 vs. 10.5 %, respectively). However, more patients with sleep apnea were in the LSG group (13.2 vs. 6.2 %, p = 0.03). The mean interval between surgery and the onset of pulmonary symptoms was longer in patients who underwent LAGB (72 ± 22 months) than for those who had LSG (36 ± 24 months; p = 0.03). The overall complication rate was higher in the LAGB (7.3 %) than in LSG (4.4 %) group. LSG patients had significantly lower rates of morning cough (12.3 vs. 59.6 %, p = 0.001) and postprandial cough (10.5 vs. 58 %, p = 0.001) compared to the LAGB patients. Two cases of pneumonia occurred in each group. The mortality rate was zero in both groups.

CONCLUSION

Both surgeries are considered safe and without major reflux-related symptoms. There is a lower incidence of cough with LSG than with LAGB.

摘要

背景

腹腔镜可调节胃束带术(LAGB)和腹腔镜袖状胃切除术(LSG)后长期的与肺反流相关的症状尚未见报道。

方法

我们设计了一项回顾性分析,纳入 2000 年 1 月至 2010 年 12 月间连续行 LAGB 或 LSG 的患者。所有患者均提供详细的病史和体格检查。我们评估了早发和迟发与反流相关的症状。所有患者均行肺功能检查和胸部 X 线(CXR)。

结果

该分析共纳入 307 例患者,其中 193 例行 LAGB,114 例行 LSG。平均年龄分别为 43±12 岁和 46±11 岁;女性分别为 144(76.6%)和 83(73%)例。两组的既往肺部疾病发生率相似(10.9% vs. 10.5%)。然而,LSG 组中睡眠呼吸暂停的患者更多(13.2% vs. 6.2%,p=0.03)。行 LAGB 术的患者发生肺部症状与手术的时间间隔较长(72±22 个月),而 LSG 组患者较短(36±24 个月;p=0.03)。LAGB 组的总体并发症发生率(7.3%)高于 LSG 组(4.4%)。LSG 患者的晨起咳嗽发生率(12.3% vs. 59.6%,p=0.001)和餐后咳嗽发生率(10.5% vs. 58%,p=0.001)明显低于 LAGB 组患者。两组各有 2 例肺炎。两组的死亡率均为零。

结论

两种手术均安全,无明显与反流相关的症状。LSG 术后咳嗽的发生率低于 LAGB。

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