Laboratoire d'électromyographie, avenue Ledru-Rollin, 75011 Paris, France.
Neurophysiol Clin. 2013 Apr;43(2):95-103. doi: 10.1016/j.neucli.2012.11.037. Epub 2012 Dec 13.
We aimed to evaluate the relative diagnostic sensitivity and specificity of different motor and sensory conduction electrodiagnostic (EDX) tests used to demonstrate ulnar neuropathy at the wrist (UNW). We also reported some data on associated nerve lesions and unusual causes of UNW.
A prospective case series was conducted in 53 cases of UNW and 100 cases of ulnar neuropathy at elbow (UNE). All cases underwent the same EDX examination according to a protocol defined in 1997. A few cases required additional conduction tests with coaxial needle recording.
The diagnostic sensitivity of the distal motor latency (DML) to adductor digiti minimi (ADM) and sensory conduction was 42% and 19% respectively. The diagnostic sensitivity of the DML to first dorsal interosseous (FDI) was 66% and studying conduction across the wrist to search for conduction block (CB) improved the diagnostic sensitivity up to 90%. In 10% of cases, no EDX test of this protocol allowed locating the site of the UNL. The specificity of each test was 100% for controls, and varied from 100% for conduction block (CB), to 95% (DML to FDI) for UNE. CB at the wrist in UNW was 2.7times more frequent than at the elbow in UNE (57% vs. 22%; P<0.0001). Finally, we found three cases of isolated sensory UNW, 16 of sensory and motor UNW, and 34 of pure motor lesions. A median nerve lesion at the wrist coexisted in 22 cases.
Improving UNW diagnosis requires systematic study of the ulnar motor conduction to FDI across the wrist, and in a few cases conduction tests with a coaxial needle recording.
评估不同的运动和感觉传导电诊断(EDX)测试在腕部尺神经病变(UNW)中的相对诊断灵敏度和特异性。我们还报告了一些与神经病变相关的资料和不常见的 UNW 病因。
前瞻性病例系列研究共纳入 53 例 UNW 患者和 100 例肘部尺神经病变(UNE)患者。所有病例均根据 1997 年制定的方案接受相同的 EDX 检查。少数病例需要进行同轴针记录的额外传导测试。
小指展肌(ADM)和感觉传导的远端运动潜伏期(DML)的诊断灵敏度分别为 42%和 19%。第一背侧骨间肌(FDI)的 DML 诊断灵敏度为 66%,研究腕部传导以寻找传导阻滞(CB)可将诊断灵敏度提高至 90%。在 10%的病例中,该方案的任何 EDX 检查均无法定位 UNL 部位。每个测试的特异性在对照组中均为 100%,从传导阻滞(CB)的 100%到肘部尺神经病变(UNE)的 95%(DML 至 FDI)不等。UNW 中腕部的 CB 比 UNE 肘部更为常见(57%比 22%;P<0.0001)。最后,我们发现 3 例孤立性感觉性 UNW、16 例感觉和运动性 UNW、34 例单纯运动性病变。22 例病例同时存在腕部正中神经病变。
提高 UNW 诊断需要系统研究腕部正中神经至 FDI 的运动传导,在少数情况下需要进行同轴针记录的传导测试。