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非恶性髂股静脉病变的血管内治疗

Endovascular management of nonmalignant iliocaval venous lesions.

作者信息

DeRubertis Brian G, Alktaifi Ali, Jimenez Juan Carlos, Rigberg David, Gelabert Hugh, Lawrence Peter F

机构信息

Division of Vascular Surgery, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, CA 90095, USA.

出版信息

Ann Vasc Surg. 2013 Jul;27(5):577-86. doi: 10.1016/j.avsg.2012.05.024. Epub 2013 Mar 26.

DOI:10.1016/j.avsg.2012.05.024
PMID:23540662
Abstract

BACKGROUND

Iliocaval venous lesions produce a spectrum of symptoms ranging from mild swelling to venous ulcerations. In this study we examine the management and outcomes of these patients at our center.

METHODS

In this study we performed a retrospective analysis of patients with symptomatic iliocaval venous stenoses, occlusions, or venous compression syndromes, who were treated with endovascular intervention during the period 2006-2010.

RESULTS

Of the 36 patients evaluated, mean age was 43.0 years; prior deep venous thrombosis (DVT), pulmonary embolism (PE), and hypercoaguable states were present in 55.5%, 25.0%, and 44.4%, respectively. Patients were stratified by the presence (group I, n = 22) or absence (group II, n = 14) of underlying May-Thurner (MT) syndrome. In group I, 11 patients had nonocclusive MT-related stenoses and 11 had acute DVT with underlying MT, causing pain/swelling (100%), venous claudication (66.7%), or CEAP class 3 (95%) or 6 (5%). Female preponderance was 2.1:1. Eighteen patients had successful intervention (angioplasty/stent with or without lysis), with clinical improvement in 94.4% and a decrease in CEAP score in 83.3%. All group II patients had chronic iliocaval occlusions causing: pain (100%); swelling (88.9%); venous claudication (44.4%); or CEAP class 3 (58%), 4 (25%), or 6 (8%). Recanalization was attempted in all patients and was successful in 71.4%. Successful recanalization was associated with clinical improvement in 88.9% and a decrease in CEAP score in 44.4%. Complications included 2 early reocclusions, 2 hematomas, and no cases of PE or death. Primary and secondary 1-year patency was 86% and 100% overall (mean follow-up 9.6 months). Primary 1-year patency for groups I and II was 87.5% and 83.3%, respectively.

CONCLUSIONS

Percutaneous intervention for chronic iliocaval venous lesions is associated with excellent 1-year patency rates and a significant reduction in symptoms and decrease in CEAP score.

摘要

背景

髂股静脉病变会引发一系列症状,从轻度肿胀到静脉溃疡不等。在本研究中,我们对本中心这些患者的治疗及结果进行了检查。

方法

在本研究中,我们对2006年至2010年期间接受血管内介入治疗的有症状的髂股静脉狭窄、闭塞或静脉压迫综合征患者进行了回顾性分析。

结果

在评估的36例患者中,平均年龄为43.0岁;既往有深静脉血栓形成(DVT)、肺栓塞(PE)和高凝状态的患者分别占55.5%、25.0%和44.4%。患者根据是否存在潜在的May-Thurner(MT)综合征分为两组(I组,n = 22;II组,n = 14)。在I组中,11例患者有非闭塞性MT相关狭窄,11例有潜在MT的急性DVT,导致疼痛/肿胀(100%)、静脉性跛行(66.7%)或CEAP分级3级(95%)或6级(5%)。女性占优势,比例为2.1:1。18例患者干预成功(血管成形术/支架置入术,伴或不伴溶栓),94.4%的患者临床症状改善,83.3%的患者CEAP评分降低。II组所有患者均有慢性髂股静脉闭塞,导致:疼痛(100%);肿胀(88.9%);静脉性跛行(44.4%);或CEAP分级3级(58%)、4级(25%)或6级(8%)。所有患者均尝试进行再通,71.4%成功。成功再通与88.9%的患者临床症状改善及44.4%的患者CEAP评分降低相关。并发症包括2例早期再闭塞、2例血肿,无PE或死亡病例。总体1年的原发和继发通畅率分别为86%和100%(平均随访9.6个月)。I组和II组1年的原发通畅率分别为87.5%和83.3%。

结论

经皮介入治疗慢性髂股静脉病变的1年通畅率良好,症状显著减轻,CEAP评分降低。

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