Royal Hobart Hospital, Department of Neurology, Hobart, Tasmania, Australia.
J Clin Neurosci. 2013 May;20(5):634-41. doi: 10.1016/j.jocn.2012.10.005. Epub 2013 Mar 26.
The role of vitamin D supplementation in preventing multiple sclerosis (MS) and/or treating MS progression is an area of significant research interest. We detail the current status of the ongoing research in this field, and note the lack of class 1 evidence from well-conducted, large, double-blind, placebo-controlled studies of vitamin D supplementation in the prevention and/or treatment of MS. We have been able to provide some guidelines for practitioners based on the substantial burden of supportive evidence for the use of vitamin D in MS as summarised here. These guidelines may provide some support to those clinicians who treat people with MS and their families.
维生素 D 补充在预防多发性硬化症 (MS) 和/或治疗 MS 进展中的作用是一个具有重要研究意义的领域。我们详细介绍了该领域正在进行的研究现状，并指出在预防和/或治疗 MS 中，缺乏来自精心设计的大型、双盲、安慰剂对照的维生素 D 补充研究的 1 类证据。我们能够根据这里总结的大量支持使用维生素 D 治疗 MS 的证据，为从业者提供一些指导方针。这些指南可能为治疗 MS 患者及其家属的临床医生提供一些支持。
