Department of Pharmacology, Mahatma Gandhi Institute of Medical Sciences, Sevagram, India.
Indian J Pharmacol. 2013 Jan-Feb;45(1):87-8. doi: 10.4103/0253-7613.106443.
Sodium valproate is a commonly used antiepileptic drug (AED) for control of a broad range of seizures. Adverse drug reactions (ADR) due to sodium valproate range from sedation to nausea, vomiting, weight gain, idiosyncratic adverse effects like hepatotoxicity and life threatening conditions like pancreatitis. We present a case of sodium valproate induced enuresis in child. This ADR of valproate is an underreported ADR and requires special attention of pediatricians as it can interfere with the further treatment of the disease.
丙戊酸钠是一种常用于控制多种癫痫发作的抗癫痫药物（AED）。丙戊酸钠的药物不良反应（ADR）从镇静到恶心、呕吐、体重增加、特发性不良反应如肝毒性，甚至危及生命的胰腺炎等。我们报告了一例丙戊酸钠引起的儿童遗尿症。丙戊酸钠的这种不良反应是一种报告较少的不良反应，需要儿科医生特别注意，因为它会干扰疾病的进一步治疗。
