Juyal Deepak, Rathaur Vyas Kumar, Sharma Neelam
Senior Demonstrator, Department of Microbiology & Immunology.
J Clin Diagn Res. 2013 Feb;7(2):369-70. doi: 10.7860/JCDR/2013/5146.2772. Epub 2012 Dec 24.
A five day old full term born baby was admitted to our Neonatal Intensive Care Unit with seizures, opisthotonous posture and was icteric upto thigh. Baby had a three day history of poor feeding, lethargy and abnormal body movements. Mother was a 29 years old primigravida and had a normal vaginal delivery at home. Sepsis profile of the patient was requested, lumbar puncture and ventricular tap was performed. Patient was put on third generation cephalosporins, aminoglycosides and phenobarbitone. Culture and sensitivity report of blood, Cerebro spinal fluid and ventricular fluid showed Proteus mirabilis. Computerized Tomography scan showed a large parenchymal lesion in the right frontal lobe and diffuse ependymal enhancement along both the lateral ventricles suggestive of meningoventriculitis. We hereby present a fatal case of neonatal meningoventriculitis due to Proteus mirabilis.
一名足月出生5天的婴儿因癫痫发作、角弓反张姿势且大腿以上黄疸被收治入我们的新生儿重症监护病房。婴儿有3天喂养困难、嗜睡及异常身体运动的病史。母亲为29岁初产妇,在家中顺产。进行了患者的败血症相关检查,实施了腰椎穿刺和脑室穿刺。患者接受了第三代头孢菌素、氨基糖苷类药物和苯巴比妥治疗。血液、脑脊液和脑室液的培养及药敏报告显示为奇异变形杆菌。计算机断层扫描显示右额叶有一个大的实质病变,双侧脑室周围有弥漫性室管膜强化,提示脑膜脑室炎。我们在此报告一例由奇异变形杆菌引起的新生儿脑膜脑室炎致死病例。