Beno I, Chorváthová V, Ovecka M
Výskumný ústav výzivy l'udu, Bratislava.
Cas Lek Cesk. 1990 May 18;129(20):609-13.
The authors investigated changes in serum lipid levels in 115 obese men and 172 obese women. The body mass index (BMI) of the subjects was 29-50 kg/m2. The group was subdivided by sex and age as follows: 15-18 years, 19-25 years, 26-35 years, 36-55 years. It was revealed that with advancing age and increasing body weight the mean tiacylglycerol levels in men increased from 1.74 mmol/l to 4.40 mmol/l, in women from 1.37 mmol/l to 1.84 mmol/l. The mean levels of total serum cholesterol increased in men from 4.58 mmol/l to 6.82 mmol/l, in women from 5.09 mmol/l to 5.96 mmol/l. In the rise of serum cholesterol in men the LDL and VLDL fractions participated, in women mainly the LDL fraction. Conversely the HDL fraction declined in men from 1.60 mmol/l to 1.20 mmol/l, in women from 1.71 mmol/l to 1.26 mmol/l. The mean value of the atherogenic index in men increased from 2.88 to 5.68, in women from 2.99 to 4.73. The results indicate the adverse changes of serum lipid levels in obese subjects which appear in men already after the age of 25 years, in women 10-20 years later. The authors discuss the causes of hyperlipoproteinaemia and the risk of atherosclerosis in obesity.
作者对115名肥胖男性和172名肥胖女性的血脂水平变化进行了调查。研究对象的体重指数（BMI）为29 - 50kg/m²。该组按性别和年龄细分如下：15 - 18岁、19 - 25岁、26 - 35岁、36 - 55岁。结果显示，随着年龄增长和体重增加，男性的平均三酰甘油水平从1.74mmol/l升至4.40mmol/l，女性从1.37mmol/l升至1.84mmol/l。男性血清总胆固醇平均水平从4.58mmol/l升至6.82mmol/l，女性从5.09mmol/l升至5.96mmol/l。男性血清胆固醇升高涉及低密度脂蛋白（LDL）和极低密度脂蛋白（VLDL）部分，女性主要是LDL部分。相反，男性高密度脂蛋白（HDL）部分从1.60mmol/l降至1.20mmol/l，女性从1.71mmol/l降至1.26mmol/l。男性动脉粥样硬化指数平均值从2.88升至5.68，女性从2.99升至4.73。结果表明，肥胖受试者血脂水平出现不良变化，男性在25岁后就已出现，女性则在10 - 20年后出现。作者讨论了肥胖中高脂蛋白血症的原因及动脉粥样硬化风险。
