Viroonudomphol Duangkamol, Pongpaew Praneet, Tungtrongchitr Rungsunn, Changbumrung Supranee, Tungtrongchitr Anchalee, Phonrat Benjaluck, Vudhivai Niyomsri, Schelp Frank P
Department of Tropical Nutrition and Food Science, Faculty of Tropical Medicine, Mahidol University, 420/6 Rajvithi Road, Rajthevee, Bangkok 10400, Thailand. v
Asia Pac J Clin Nutr. 2003;12(1):73-9.
The weight, height, body mass index (BMI), waist/hip ratio, serum retinol and alpha-tocopherol and lipid profiles of 16 overweight (BMI > or = 25.0 kg/m2) Thai males and 56 overweight females, compared with 14 males and 58 females in a control group (BMI 18.5-24.9 kg/m2), were investigated. Subjects for the study were those persons who turned up regularly for physical check-up at the Outpatient Department, General Practice Section of Rajvithi Hospital, Bangkok. The study was conducted between December 2000-March 2001. Higher levels of cholesterol, LDL-C, LDL-C/HDL-C ratio were found in the overweight compared with the control subjects. Statistically significant higher triglyceride levels were found in the overweight compared with the control subjects. The median serum retinol concentration in overweight subjects was 2.80 mumol/L (range 0.53-4.62 mumol/L) compared with 2.97 mumol/L (range 1.21-4.12 mumol/L) in control subjects (p = 0.0736). The median serum alpha-tocopherol concentration in overweight subjects was 17.30 mumol/L (range 6.29-28.65 mumol/L) compared with 18.75 mumol/L (range 5.30-30.28 mumol/L) in control subjects (P < 0.05). The median values of retinol and alpha-tocopherol serum concentrations in the overweight and obese males were lower than those of the overweight and obese females. A total of 6.3% (1 out of 16) and 12.5% (2 out of 16) of the overweight/obese males had decreased retinol and alpha-tocopherol levels, while the overweight/obese females had decreased retinol and alpha-tocopherol level of 1.8% (1 out of 56) and 10.7% (6 out of 56), respectively. A total of 12.5% and 39.3% of the overweight/obese males and females had cholesterol concentrations of > or = 6.48 mmol/l. However, the prevalence of low HDL-C (HDL-C < or = 0.91 mmol/l) was found to be 50% in the overweight and obese males and 10.7% in the overweight and obese females. Statistically significant associations were found between age, cholesterol, LDL-C, and serum alpha-tocopherol in the overweight and obese male and female subjects. A negative correlation was found between weight, BMI, AC, MAMC, hip circumference and serum retinol in both the overweight and obese subjects. A negative correlation was found between weight, BMI, MAMC, waist, hip circumferences and serum alpha-tocopherol in both the overweight and obese subjects.
对16名超重（体重指数≥25.0kg/m²）的泰国男性和56名超重女性进行了体重、身高、体重指数（BMI）、腰臀比、血清视黄醇、α-生育酚和血脂谱的调查，并与对照组的14名男性和58名女性（BMI 18.5 - 24.9kg/m²）进行比较。研究对象为定期到曼谷拉吉维蒂医院全科门诊进行体检的人员。该研究于2000年12月至2001年3月进行。与对照组相比，超重者的胆固醇、低密度脂蛋白胆固醇（LDL-C）、LDL-C/高密度脂蛋白胆固醇（HDL-C）比值水平更高。与对照组相比，超重者的甘油三酯水平在统计学上有显著升高。超重者血清视黄醇浓度中位数为2.80μmol/L（范围0.53 - 4.62μmol/L），而对照组为2.97μmol/L（范围1.21 - 4.12μmol/L）（p = 0.0736）。超重者血清α-生育酚浓度中位数为17.30μmol/L（范围6.29 - 28.65μmol/L），对照组为18.75μmol/L（范围5.30 - 30.28μmol/L）（P < 0.05）。超重和肥胖男性的视黄醇和α-生育酚血清浓度中位数低于超重和肥胖女性。超重/肥胖男性中分别有6.3%（16人中的1人）和12.5%（16人中的2人）视黄醇和α-生育酚水平降低，而超重/肥胖女性中视黄醇和α-生育酚水平降低的比例分别为1.8%（56人中的1人）和10.7%（56人中的6人）。超重/肥胖男性和女性中分别有12.5%和39.3%的胆固醇浓度≥6.48mmol/l。然而，超重和肥胖男性中低HDL-C（HDL-C≤0.91mmol/l）的患病率为50%，超重和肥胖女性中为10.7%。在超重和肥胖的男性和女性受试者中，年龄、胆固醇、LDL-C和血清α-生育酚之间存在统计学上的显著关联。在超重和肥胖受试者中，体重、BMI、臂围、腰围、臀围与血清视黄醇之间均呈负相关。在超重和肥胖受试者中，体重、BMI、腰围、臀围与血清α-生育酚之间均呈负相关。
