Université de Lyon, ENTPE, CNRS, UMR 5023 LEHNA, 2 Rue Maurice Audin, 69518 Vaulx-en-Velin, France.
Sci Total Environ. 2013 Jun 1;454-455:250-76. doi: 10.1016/j.scitotenv.2013.02.064. Epub 2013 Mar 29.
The multiple activities that take place in hospitals (surgery, drug treatments, radiology, cleaning of premises and linen, chemical and biological analysis laboratories, etc.), are a major source of pollutant emissions into the environment (disinfectants, detergents, drug residues, etc.). Most of these pollutants can be found in hospital effluents (HWW), then in urban sewer networks and WWTP (weakly adapted for their treatment) and finally in aquatic environments. In view to evaluating the impact of these pollutants on aquatic ecosystems, it is necessary to characterise their ecotoxicity. Several reviews have focused on the quantitative and qualitative characterisation of pollutants present in HWW. However, none have focused specifically on the characterisation of their experimental ecotoxicity. We have evaluated this according to two complementary approaches: (i) a "substance" approach based on the identification of the experimental data in the literature for different substances found in hospital effluents, and on the calculation of their PNEC (Predicted Non Effect Concentration), (ii) a "matrix" approach for which we have synthesised ecotoxicity data obtained from the hospital effluents directly. This work first highlights the diversity of the substances present within hospital effluents, and the very high ecotoxicity of some of them (minimum PNEC observed close to 0,01 pg/L). We also observed that the consumption of drugs in hospitals was a predominant factor chosen by authors to prioritise the compounds to be sought. Other criteria such as biodegradability, excretion rate and the bioaccumulability of pollutants are considered, though more rarely. Studies of the ecotoxicity of the particulate phase of effluents must also be taken into account. It is also necessary to monitor the effluents of each of the specialised departments of the hospital studied. These steps is necessary to define realistic environmental management policies for hospitals (replacement of toxic products by less pollutant ones, etc.).
医院中的多种活动(手术、药物治疗、放射学、场所和衣物清洁、化学和生物分析实验室等)是污染物排放到环境中的主要来源(消毒剂、清洁剂、药物残留等)。这些污染物中的大多数都可以在医院废水中(HWW)找到,然后在城市污水管网和 WWTP(处理能力较弱)中找到,最后在水生环境中找到。为了评估这些污染物对水生生态系统的影响,有必要对其生态毒性进行特征描述。有几篇综述集中于对 HWW 中存在的污染物进行定量和定性特征描述。然而,没有一篇专门关注对其实验生态毒性的特征描述。我们根据两种互补的方法对此进行了评估:(i)基于文献中对医院废水中不同物质的实验数据的识别的“物质”方法,并计算其 PNEC(预测无效应浓度),(ii)“基质”方法,其中我们综合了直接从医院废水中获得的生态毒性数据。这项工作首先强调了医院废水中存在的物质的多样性,以及其中一些物质的极高生态毒性(观察到的最低 PNEC 接近 0.01pg/L)。我们还观察到,医院中药物的使用是作者选择优先寻找化合物的主要因素。其他标准,如污染物的可生物降解性、排泄率和生物累积性,也被考虑到,尽管更少见。还必须考虑到废水中颗粒相的生态毒性研究。有必要对所研究医院的每个专门部门的废水进行监测。这些步骤对于制定医院的现实环境管理政策(用污染较小的产品替代有毒产品等)是必要的。