Gayathri R, Chandni R, Udayabhaskaran V
KMCT Medical College, Dept. of Medicine, Mukkam, Calicut.
J Assoc Physicians India. 2012 Sep;60:20-4.
The present study was carried out to study the correlation between carotid artery intima media thickness (CIMT) with risk factors for atherosclerosis and atherosclerotic events in Type 2 Diabetes mellitus patients. The predictive value of CIMT as an indicator of early atherosclerosis was determined and the various atherosclerotic risk factors in type 2 diabetes mellitus were studied. Our study showed that CIMT was significantly higher in those type 2 diabetic patients who had atherosclerotic events than in those patients who had no atherosclerotic events. It was also found that waist hip ratio showed a significant positive correlation and independent association with CIMT emphasizing the emerging concept of central obesity. Duration of diabetes, urinary albumin excretion rate, hypertension and glycated hemoglobin had positive correlation with CIMT, but could not assume statistical significance. Age, smoking and dyslipidemia did not show any association with CIMT.
本研究旨在探讨2型糖尿病患者颈动脉内膜中层厚度(CIMT)与动脉粥样硬化危险因素及动脉粥样硬化事件之间的相关性。确定了CIMT作为早期动脉粥样硬化指标的预测价值,并研究了2型糖尿病患者的各种动脉粥样硬化危险因素。我们的研究表明,发生动脉粥样硬化事件的2型糖尿病患者的CIMT显著高于未发生动脉粥样硬化事件的患者。还发现腰臀比与CIMT呈显著正相关且独立相关,强调了中心性肥胖这一新兴概念。糖尿病病程、尿白蛋白排泄率、高血压和糖化血红蛋白与CIMT呈正相关,但无统计学意义。年龄、吸烟和血脂异常与CIMT无任何关联。