Bardin E D, Krieger J N
Department of Urology, University of Washington, School of Medicine, Seattle.
Int Urol Nephrol. 1990;22(2):147-52. doi: 10.1007/BF02549833.
Priapism occurred in ten patients undergoing treatment of depression with trazodone or impotence with papaverine. Trazodone-related priapism uniformly required surgical procedures and resulted in impotence in two of three cases. In contrast, papaverine-associated priapism was successfully managed by aspiration and all seven patients continued to respond to intracorporal treatment. Iatrogenic priapism is an important complication of therapy with vasoactive drugs.
10名正在接受曲唑酮治疗抑郁症或罂粟碱治疗阳痿的患者发生了阴茎异常勃起。与曲唑酮相关的阴茎异常勃起均需手术治疗，3例中有2例导致阳痿。相比之下，与罂粟碱相关的阴茎异常勃起通过抽吸成功处理，所有7例患者继续对体内治疗有反应。医源性阴茎异常勃起是血管活性药物治疗的重要并发症。
