Dickerman J L
J Am Osteopath Assoc. 1990 May;90(5):456-8.
The author presents the case history of an obese patient in whom gallstones developed 5 months after she began a weight-loss program. Conservative management with chenodeoxycholic acid completely resolved cholelithiasis following four months of treatment. Gallstone-formation has traditionally been attributed to supersaturation of bile with cholesterol. However, the author proposes that the formation of gallstones may also be related to a change in gallbladder mechanics stimulated by dieting over an extended period. Recognition of this risk can lead to early diagnosis of gallstones, thus enhancing effective treatment by conservative methods.
作者介绍了一位肥胖患者的病史，该患者在开始减肥计划5个月后出现胆结石。采用鹅去氧胆酸进行保守治疗，四个月后胆结石完全消失。传统上认为胆结石的形成是由于胆汁中胆固醇过度饱和。然而，作者提出胆结石的形成也可能与长期节食刺激胆囊力学改变有关。认识到这种风险可导致胆结石的早期诊断，从而通过保守方法提高治疗效果。
