Yashpal M, Kumari U, Mittal S, Mittal A K
Skin Physiology Laboratory, Centre of Advanced Study, Department of Zoology, Banaras Hindu University, Varanasi, 221 005, Uttar Pradesh, India; Electron Microscope Facility, Department of Anatomy, Institute of Medical Sciences, Banaras Hindu University, Varanasi, 221 005, Uttar Pradesh, India.
Anat Histol Embryol. 2014 Apr;43(2):116-32. doi: 10.1111/ahe.12055. Epub 2013 Apr 4.
Glycoproteins (GPs) were visualized histochemically in the secretory cells - the mucous goblet cells (the type A and the type B), the rodlet cells and the epithelial cells in different regions of the buccal cavity of Cirrhinus mrigala. The type A mucous goblet cells, the type B mucous goblet cells, the rodlet cells and the epithelial cells elaborate GPs with oxidizable vicinal diols and GPs with sialic acid residue without O-acyl substitution. The type A mucous goblet cells, in addition, contain moderate amounts of GPs with O-sulphate esters. The type B mucous goblet cells, in contrast, contain high concentrations of GPs with O-sulphate esters. The rodlet cells secrete small amounts of GPs with oxidizable vicinal diols. The analysis of the results elucidates interesting differences in the composition and concentration of GPs in the mucus elaborated by the secretory cells indicating the potential importance of the glycoproteins in the buccal cavity. These GPs could be considered to represent a mechanism for modulation of the composition of the protective mucus layer correlated to specific functions.
在印度鲮口腔不同区域的分泌细胞（即黏液杯状细胞-A型和B型、小棒状细胞及上皮细胞）中，通过组织化学方法观察到了糖蛋白（GPs）。A型黏液杯状细胞、B型黏液杯状细胞、小棒状细胞及上皮细胞能合成具有可氧化邻二醇的糖蛋白以及不含O-酰基取代的含唾液酸残基的糖蛋白。此外，A型黏液杯状细胞还含有适量带O-硫酸酯的糖蛋白。相比之下，B型黏液杯状细胞含有高浓度带O-硫酸酯的糖蛋白。小棒状细胞分泌少量具有可氧化邻二醇的糖蛋白。对结果的分析揭示了分泌细胞分泌的黏液中糖蛋白在组成和浓度上存在有趣的差异，这表明糖蛋白在口腔中具有潜在的重要性。这些糖蛋白可被视为一种调节与特定功能相关的保护性黏液层组成的机制。
