Hammond R L, Bridges C R, DiMeo F, Stephenson L W
Harrison Department of Surgical Research, University of Pennsylvania Medical School, Philadelphia.
J Heart Transplant. 1990 May-Jun;9(3 Pt 1):252-7.
Skeletal muscle ventricles were constructed in 12 dogs. In one group of dogs (n = 7) the skeletal muscle ventricles were constructed around a 17 ml Teflon mandrel, and in the other group (n = 5) a 45 ml mandrel was used. Use of the larger mandrel resulted in an increase in compliance and greater stroke work over the physiologic range of preloads and afterloads. With the larger mandrel, stroke work consistently exceeded normal canine stroke work at physiologic filling pressures.
在12只犬身上构建了骨骼肌心室。在一组犬（n = 7）中，围绕一个17毫升的聚四氟乙烯心轴构建骨骼肌心室，而在另一组（n = 5）中使用了一个45毫升的心轴。使用较大的心轴导致在生理前负荷和后负荷范围内顺应性增加且每搏功更大。使用较大的心轴时，在生理充盈压下每搏功持续超过正常犬的每搏功。
