Center for Soft Matter Research, New York University, New York, NY 10003, USA.
Adv Mater. 2013 May 28;25(20):2779-83. doi: 10.1002/adma.201204864. Epub 2013 Apr 3.
A simple and effective way to make DNA patchy particles is reported. A small patch of DNA strands is "stamped" from a gold surface onto colloidal particles of different sizes by streptavidin-biotin bonds. These DNA patchy particles provide direction-selective and thermoreversible interactions, and hence can lead to unique assembly protocols and structures controlled by temperature.
报道了一种简单有效的方法来制备 DNA 有缺陷的粒子。通过链霉亲和素-生物素键,一小段 DNA 链从金表面“压印”到不同大小的胶体颗粒上,形成 DNA 有缺陷的粒子。这些 DNA 有缺陷的粒子提供了方向选择性和热可逆相互作用,因此可以导致独特的组装方案和由温度控制的结构。