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Phosphorylation of AMPA-type glutamate receptors: the trigger of epileptogenesis?

作者信息

Bakker Joanne, Basedow Frederike J, Dekker Alain D, Papantoniou Christos

机构信息

Department of Molecular Neurobiology, Graduate School of Behavioural and Cognitive Neurosciences, University of Groningen and University Medical Center Groningen, Nijenborgh 7, 9747 AG Groningen, The Netherlands.

出版信息

J Neurosci. 2013 Apr 3;33(14):5879-80. doi: 10.1523/JNEUROSCI.0496-13.2013.

DOI:10.1523/JNEUROSCI.0496-13.2013
PMID:23554469
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6618943/
Abstract
摘要

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本文引用的文献

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Glutamate receptor 1 phosphorylation at serine 831 and 845 modulates seizure susceptibility and hippocampal hyperexcitability after early life seizures.谷氨酸受体 1 丝氨酸 831 和 845 的磷酸化调节早期癫痫发作后癫痫易感性和海马过度兴奋。
J Neurosci. 2012 Dec 5;32(49):17800-12. doi: 10.1523/JNEUROSCI.6121-11.2012.
2
Impaired autophagy in neurons after disinhibition of mammalian target of rapamycin and its contribution to epileptogenesis.神经元中雷帕霉素靶蛋白去抑制后自噬受损及其在癫痫发生中的作用。
J Neurosci. 2012 Nov 7;32(45):15704-14. doi: 10.1523/JNEUROSCI.2392-12.2012.
3
Neuronal stimulation induces autophagy in hippocampal neurons that is involved in AMPA receptor degradation after chemical long-term depression.神经元刺激诱导海马神经元自噬，该自噬参与化学性长时程压抑后 AMPA 受体降解。
J Neurosci. 2012 Jul 25;32(30):10413-22. doi: 10.1523/JNEUROSCI.4533-11.2012.
4
Brain area specific regulation of synaptic AMPA receptors by phosphorylation.磷酸化对突触AMPA受体的脑区特异性调节。
Commun Integr Biol. 2011 Sep;4(5):569-72. doi: 10.4161/cib.4.5.15890. Epub 2011 Sep 1.
5
Genetic deletion of TNF receptor suppresses excitatory synaptic transmission via reducing AMPA receptor synaptic localization in cortical neurons.基因敲除 TNF 受体通过减少皮质神经元中 AMPA 受体的突触定位来抑制兴奋性突触传递。
FASEB J. 2012 Jan;26(1):334-45. doi: 10.1096/fj.11-192716. Epub 2011 Oct 7.
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