Zheng Qi, Nan Kejun, Yao Yu
Department of Medical Oncology, the First Affiliated Hospital, Xi'an Jiaotong University, Xi'an, Shaanxi 710061, China.
J Biomed Res. 2012 Jul;26(4):303-6. doi: 10.7555/JBR.26.20110056. Epub 2012 Apr 15.
Bone metastasis of gastric cancer is relatively uncommon in clinical practice. Moreover, it is all the more unusual for the primary presentation of gastric malignancy to be bone metastasis. Here, we describe a male patient who complained of pain and edema in his right lower extremity. Further assessment by computed tomography and positron emission tomography revealed an abnormally thickened gastric cardia and a giant neoplasm in the right pelvis with bone damage. Consequently, the finding of adenocarcinoma cells in pelvic and cardia biopsy specimens contributed to the diagnosis of pelvic metastasis from gastric cancer. This case report illustrates that stomach cancer has the potential, although far less than breast, prostate and lung cancers, to metastasize to bone. In addition, it highlights the peculiarity of this bone metastasis which is pelvic, solitary and huge.
在临床实践中,胃癌骨转移相对少见。此外,胃癌以骨转移作为首发表现则更为罕见。在此,我们描述一位男性患者,他主诉右下肢疼痛和水肿。通过计算机断层扫描和正电子发射断层扫描进一步评估发现,胃贲门异常增厚,右盆腔有一个巨大肿瘤并伴有骨质破坏。因此,在盆腔和贲门活检标本中发现腺癌细胞有助于诊断为胃癌盆腔转移。本病例报告表明,胃癌虽远不及乳腺癌、前列腺癌和肺癌那样容易发生骨转移,但仍有发生骨转移的可能。此外,它还突出了这种骨转移的特殊性,即发生在盆腔、为孤立性且肿瘤巨大。