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新皮质和海马体激活与行为的关系:阿托品、毒扁豆碱、吩噻嗪类药物及苯丙胺的影响。

Neocortical and hippocampal activation relation to behavior: effects of atropine, eserine, phenothiazines, and amphetamine.

作者信息

Vanderwolf C H

出版信息

J Comp Physiol Psychol. 1975 Jan;88(1):300-23. doi: 10.1037/h0076211.

DOI:10.1037/h0076211
PMID:235571
Abstract

Evidence is presented to suggest that the hippocampus receives 2 nonspecific inputs from the brainstem, each capable of producing rhythmical slow activity. The neocortex appears to receive 2 similar inputs, each capable of producing low voltage fast activity. One input to both hippocampus and neocortex is blocked by atropine and stimulated by eserine, and is essentially unrelated to concurrent motor activity. A second input to both hippocampus and neocortex is resistant to atropine, is depressed by phenothiazines, and is activated by d-amphetamine. Activity in this system is closely related to concurrent "voluntary" movement.

摘要

有证据表明,海马体从脑干接收两种非特异性输入,每种输入都能够产生节律性慢活动。新皮层似乎也接收两种类似的输入,每种输入都能够产生低电压快活动。海马体和新皮层的一种输入被阿托品阻断,被毒扁豆碱刺激,并且基本上与同时发生的运动活动无关。海马体和新皮层的第二种输入对阿托品有抗性,被吩噻嗪类药物抑制,并被d-苯丙胺激活。该系统中的活动与同时发生的“随意”运动密切相关。

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