Krause Cornelia, Richter Sandra, Knöll Christian, Jürgens Gerd
Center for Plant Molecular Biology (ZMBP), University of Tübingen, Auf der Morgenstelle 3, 72076 Tübingen, Germany.
Biochim Biophys Acta. 2013 Nov;1834(11):2429-41. doi: 10.1016/j.bbapap.2013.03.024. Epub 2013 Apr 2.
Recent studies suggest that plants secrete a large number of proteins and peptides into the extracellular space. Secreted proteins play a crucial role in stress response, communication and development of organisms. Here we review the current knowledge of the secretome of more than ten plant species, studied in natural conditions or during (a)biotic stress. This review not only deals with the classical secretory route via endoplasmic reticulum and Golgi followed by proteins containing a known N-terminal signal peptide, but also covers new findings about unconventional secretion of leaderless proteins. We describe alternative secretion pathways and the involved compartments like the recently discovered EXPO. The well characterized secreted peptides that function as ligands of receptor proteins exemplify the biological significance and activity of the secretome. This article is part of a Special Issue entitled: An Updated Secretome.
最近的研究表明，植物会向细胞外空间分泌大量蛋白质和肽。分泌蛋白在生物体的应激反应、通讯及发育过程中发挥着关键作用。在此，我们综述了在自然条件下或（非）生物胁迫期间对十多种植物物种分泌组的现有认识。本综述不仅涉及经由内质网和高尔基体的经典分泌途径以及含有已知N端信号肽的蛋白质，还涵盖了关于无信号肽蛋白质非传统分泌的新发现。我们描述了替代分泌途径以及所涉及的区室，如最近发现的EXPO。作为受体蛋白配体发挥作用的、特征明确的分泌肽例证了分泌组的生物学意义和活性。本文是名为《更新后的分泌组》特刊的一部分。
