Institut de Veille Sanitaire, Saint Maurice cedex, France.
Euro Surveill. 2013 Mar 21;18(12):20434.
The proportion of patients considered to be cured is a key indicator to assess national tuberculosis (TB) control. In France, TB treatment outcome monitoring was implemented in 2007. This article presents national results on treatment outcome among patients with pulmonary TB reported in France in 2009 and explores determinants of potentially unfavourable outcome. Information on treatment outcome was reported for 63% of eligible pulmonary cases of whom 70% had a successful outcome. In a multivariate analysis, potentially unfavourable outcome (17%), compared to treatment success, was significantly associated with being male, born abroad and having lived in France for less than 10 years, being in congregate settings when treatment was initiated, or having a previous history of anti-TB treatment. Enhanced awareness of treatment outcome monitoring is essential to improve the coverage and the quality of information. Earlier diagnosis and improved management of the disease in the elderly may reduce death due to TB. The high proportion of potentially unfavourable outcomes should be further investigated as they may require additional vigilance and/or actions in term of efforts of TB control in some population groups.
治愈患者的比例是评估国家结核病（TB）控制情况的关键指标。法国于 2007 年开始实施结核病治疗结果监测。本文介绍了 2009 年法国报告的肺结核患者治疗结果的全国性结果，并探讨了可能不良结局的决定因素。2009 年，63%的符合条件的肺结核病例报告了治疗结果，其中 70%的患者治疗成功。在多变量分析中，与治疗成功相比，可能出现不良结局（17%）与男性、在国外出生、在法国居住不到 10 年、治疗开始时处于集体环境或以前有抗结核治疗史显著相关。提高对治疗结果监测的认识对于提高覆盖率和信息质量至关重要。更早地诊断和改善老年人的疾病管理可以减少因结核病而导致的死亡。应进一步调查可能出现的不良结局比例较高的情况，因为这可能需要在某些人群中加强结核病控制工作的警惕性和/或采取行动。
