Department of Psychology, L.L. Thurstone Psychometric Laboratory, UNC-Chapel Hill.
J Subst Abuse Treat. 2013 Aug;45(2):179-89. doi: 10.1016/j.jsat.2013.01.015. Epub 2013 Apr 1.
The Recovery Management paradigm provides a conceptual framework for the examination of joint impact of a focal treatment and post-treatment service utilization on substance abuse treatment outcomes. We test this framework by examining the interactive effects of a treatment for comorbid PTSD and substance use, Seeking Safety, and post-treatment Twelve-Step Affiliation (TSA) on alcohol and cocaine use.
Data from 353 women in a six-site, randomized controlled effectiveness trial within the NIDA Clinical Trials Network were analyzed under latent class pattern mixture modeling. LCPMM was used to model variation in Seeking Safety by TSA interaction effects on alcohol and cocaine use.
Significant reductions in alcohol use among women in Seeking Safety (compared to health education) were observed; women in the Seeking Safety condition who followed up with TSA had the greatest reductions over time in alcohol use. Reductions in cocaine use over time were also observed but did not differ between treatment conditions nor were there interactions with post-treatment TSA.
Findings advance understanding of the complexities for treatment and continuing recovery processes for women with PTSD and SUDs, and further support the chronic disease model of addiction.
康复管理范式为研究焦点治疗和治疗后服务利用对物质滥用治疗结果的联合影响提供了一个概念框架。我们通过检验治疗共病创伤后应激障碍和物质使用的寻求安全治疗,以及治疗后十二步隶属关系(TSA)对酒精和可卡因使用的相互作用效应,来检验这一框架。
在 NIDA 临床试验网络的 6 个地点的随机对照有效性试验中,对 353 名女性的数据进行了潜在类别模式混合建模分析。LCPMM 用于对 TSA 寻求安全的相互作用对酒精和可卡因使用的影响进行建模。
与健康教育相比,寻求安全的女性的酒精使用量显著减少;在寻求安全条件下并随后加入 TSA 的女性,其酒精使用量随着时间的推移而减少最多。可卡因使用量也随着时间的推移而减少,但在治疗条件之间没有差异,也没有与治疗后 TSA 的相互作用。
这些发现推进了对女性 PTSD 和 SUD 治疗和持续康复过程复杂性的理解,并进一步支持成瘾的慢性疾病模型。