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高龄老人中的痴呆症

Dementia in the oldest old.

作者信息

Bullain Szófia S, Corrada María M

机构信息

University of California, Irvine, 1513 Hewitt Hall, Irvine, CA 92697,

出版信息

Continuum (Minneap Minn). 2013 Apr;19(2 Dementia):457-69. doi: 10.1212/01.CON.0000429172.27815.3f.

Abstract

PURPOSE OF REVIEW

This article discusses some of the unique features of dementia in the oldest old, including some of the most common diagnostic challenges, and potential strategies to overcome them.

RECENT FINDINGS

Advances include new insight into the role of common risk factors and the effects of multiple underlying neuropathologic features for dementia in the oldest old. In addition, this article contains the latest age-specific normative data for commonly used neuropsychological tests for the oldest old.

SUMMARY

The oldest old-people aged 90 years and older-are the fastest-growing segment of society and have the highest rates of dementia in the population. The risk factors, diagnostic challenges, and underlying neuropathologic features of dementia are strikingly different in the 90-years-and-older population compared to younger elderly. Special consideration of these unique features of dementia is necessary when evaluating oldest-old subjects with cognitive impairment.

摘要

综述目的

本文讨论了高龄老年人痴呆症的一些独特特征,包括一些最常见的诊断挑战以及克服这些挑战的潜在策略。

最新发现

进展包括对常见风险因素的作用以及多种潜在神经病理特征对高龄老年人痴呆症影响的新认识。此外,本文包含了针对高龄老年人常用神经心理测试的最新特定年龄规范数据。

总结

90岁及以上的高龄老年人是社会中增长最快的群体,且其痴呆症发病率在人群中最高。与年轻老年人相比,90岁及以上人群中痴呆症的风险因素、诊断挑战和潜在神经病理特征存在显著差异。在评估有认知障碍的高龄老年人时,有必要特别考虑痴呆症的这些独特特征。

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