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股动脉病变中的药物洗脱技术。

Drug-eluting technologies in femoral artery lesions.

作者信息

Deloose K, Lauwers K, Callaert J, Maene L, Keirse K, Verbist J, Peeters P, Bosiers M

机构信息

Departement Vascular Surgery, A.Z. Sint‑Blasius, Dendermonde, Belgium.

出版信息

J Cardiovasc Surg (Torino). 2013 Apr;54(2):217-24.

Abstract

The treatment of femoropopliteal lesions has known an important evolution in the last years. An important limitation of current endovascular therapy remains the occurrence of restenosis. In order to minimize restenosis rates, drug eluting technologies are evolving. The use of drug-eluting stents (DES) in coronary arteries shows beneficial results, leading to investigation of DES in femoropopliteal arteries. In this article, we give an overview of current available data on treatment with drug eluting technologies in the superficial femoral artery (SFA). This paper summarizes also the current available data of the use of drug-coated balloons (DCB) in the femoropopliteal tract. Currently, no data are available on the use of DCB in long lesions. A drug eluting bioresorbable scaffold seems to be very promising in coronary arteries. The transfer to the peripheral area is nowadays ongoing. Which technique and device for which lesion and patient requires further investigation to build up a real evidence based SFA treatment strategy.

摘要

在过去几年中,股腘动脉病变的治疗取得了重大进展。目前血管内治疗的一个重要局限性仍然是再狭窄的发生。为了将再狭窄率降至最低,药物洗脱技术正在不断发展。冠状动脉中药物洗脱支架(DES)的使用显示出有益的结果,这促使人们对股腘动脉中的DES进行研究。在本文中,我们概述了目前关于股浅动脉(SFA)药物洗脱技术治疗的可用数据。本文还总结了股腘动脉段使用药物涂层球囊(DCB)的现有数据。目前,尚无关于DCB用于长病变的相关数据。药物洗脱生物可吸收支架在冠状动脉中似乎非常有前景。目前正在向周边领域推广。对于何种病变和患者应采用何种技术和器械,仍需进一步研究,以建立基于真实证据的SFA治疗策略。

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