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双侧经皮腔内肾动脉成形术治疗双侧临界性肾动脉狭窄患者的疗效和效果。

Outcomes and effectiveness of bilateral percutaneous transluminal renal artery stenting in patients with critical bilateral renal artery stenosis.

出版信息

Cardiol J. 2013;20(1):25-8. doi: 10.5603/CJ.2013.0005.

Abstract

BACKGROUND

The aim of this study was to assess the effects of percutaneous bilateral renal artery stenting in patients with atherosclerotic renal artery stenosis and in-hospital and 4 month outcome of the procedure, focusing on the changes in renal function and blood pressure.

METHODS

Five consecutive patients (mean age: 64.8 ± 9.7 years, 1 women) with bilateral renal artery stenoses underwent percutaneous interventions. We compared blood pressure, number of oral antihypertensive medications, and renal function changes preprocedure and postprocedure at 4 months follow-up.

RESULTS

A total of 5 bilateral atherosclerotic renal artery stenosis patients underwent percutaneous transluminal renal angioplasty and 10 stents were placed. Although systolic and diastolic blood pressures were significantly decreased in follow-up period, glomerular filtration rates were not significantly changed as compared with baseline data (p = 0.009, p = 0.008, p = 1.00, respectively). Also, the number of oral antihypertensive medications were significantly decreased at follow-up period (p = 0.03).

CONCLUSIONS

Bilateral renal artery stenting provides a beneficial outcome such as stabilization of renal functions, significant improvement in blood pressure control and reduction in the number of oral antihypertensive medications at follow-up.

摘要

背景

本研究旨在评估经皮双侧肾动脉支架置入术治疗粥样硬化性肾动脉狭窄患者的效果,以及住院期间和术后 4 个月的结果,重点关注肾功能和血压的变化。

方法

连续 5 例(平均年龄:64.8 ± 9.7 岁,女性 1 例)双侧肾动脉狭窄患者接受了经皮介入治疗。我们比较了术前和术后 4 个月时血压、口服降压药物的数量以及肾功能的变化。

结果

共 5 例双侧粥样硬化性肾动脉狭窄患者接受了经皮腔内肾血管成形术,共放置了 10 个支架。尽管随访期间收缩压和舒张压均显著降低,但与基线数据相比,肾小球滤过率无明显变化(p = 0.009,p = 0.008,p = 1.00,分别)。此外,随访期间口服降压药物的数量也显著减少(p = 0.03)。

结论

双侧肾动脉支架置入术可带来有益的结果,如肾功能稳定、血压控制显著改善以及随访期间口服降压药物的数量减少。

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