Barry D T, Gordon K E, Hinton G G
Department of Physical Medicine and Rehabilitation, University of Michigan Medical Center, Ann Arbor 48109-0042.
Muscle Nerve. 1990 Apr;13(4):286-90. doi: 10.1002/mus.880130403.
The ratio of acoustic myography (AMG) amplitude to surface electromyography (EMG) amplitude is proposed as a measure of mechanical output compared with electrical activity of the contractile system. AMG to EMG ratios were measured from 16 children with muscle disease diagnosed by clinical criteria, EMG, and/or muscle biopsy. These were compared with the ratios from 11 normal volunteers spanning the same age range (7-16 years). AMG to EMG ratios were significantly (P less than 0.01) different for the two populations. Using a linear discriminant function to define the normal range for AMG to EMG ratios yielded a sensitivity of 82% (13 of 16 abnormals diagnosed) and a specificity of 91% (10 of 11 normals). These findings suggest that surface recordings may provide significant diagnostic information in muscle disease. The accuracy may be improved further by using additional muscles (e.g., paraspinals) and evoked twitches.
