Kshirsagar V Y, Nagarsenkar Suhel, Ahmed Minhajuddin, Colaco Sylvia, Wingkar K C
Department of Pediatrics, Krishna Institute of Medical Sciences University, Krishna Hospital, Karad, Maharashtra, India.
J Pediatr Neurosci. 2012 Sep;7(3):163-6. doi: 10.4103/1817-1745.106468.
Abdominal epilepsy (AE) is an uncommon cause for chronic recurrent abdominal pain in children and adults. It is characterized by paroxysmal episode of abdominal pain, diverse abdominal complaints, definite electroencephalogram (EEG) abnormalities and favorable response to the introduction of anti-epileptic drugs (AED). We studied 150 children with chronic recurrent abdominal pain and after exclusion of more common etiologies for the presenting complaints; workup proceeded with an EEG. We found 111 (74%) children with an abnormal EEG and 39 (26%) children with normal EEG. All children were subjected to AED (Oxcarbazepine) and 139 (92%) children responded to AED out of which 111 (74%) children had an abnormal EEG and 27 (18%) had a normal EEG. On further follow-up the patients were symptom free, which helped us to confirm the clinical diagnosis.
Recurrent chronic abdominal pain is a common problem encountered by pediatricians. Variety of investigations are done to come to a diagnosis but a cause is rarely found. In such children diagnosis of AE should be considered and an EEG will confirm the diagnosis and treated with AED.
To find the incidence of AE in children presenting with chronic recurrent abdominal pain and to correlate EEG findings and their clinical response to empirical AEDs in both cases and control.
Krishna Institute of Medical Sciences University, Karad, Maharashtra, India. Prospective analytical study.
A total of 150 children with chronic recurrent abdominal pain were studied by investigations to rule out common causes of abdominal pain and an EEG. All children were then started with AED oxycarbamezepine and their response to the treatment was noted.
111 (74%) of the total 150 children showed a positive EEG change suggestive of epileptogenic activity and of which 75 (67.56%) were females and 36 (32.43%) were male, majority of children were in the age of group of 9-12 years. Temporal wave discharges were 39 (35.13%) of the total abnormal EEG's. All the children were started on AEDs and those with abnormal EEG showed 100% response to treatment while 27 (18%) children with normal EEG also responded to treatment. Twelve (8%) children did not have any improvement in symptoms.
A diagnosis of AE must be considered in children with chronic recurrent abdominal pain, especially in those with suggestive history, and an EEG can save a child from lot of unnecessary investigations and suffering.
腹型癫痫（AE）是儿童和成人慢性复发性腹痛的一种少见病因。其特征为阵发性腹痛发作、多样的腹部不适、明确的脑电图（EEG）异常以及对抗癫痫药物（AED）治疗反应良好。我们研究了150例患有慢性复发性腹痛的儿童，在排除了更常见的主诉病因后；进行了脑电图检查。我们发现111例（74%）儿童脑电图异常，39例（26%）儿童脑电图正常。所有儿童均接受了AED（奥卡西平）治疗，139例（92%）儿童对AED有反应，其中111例（74%）儿童脑电图异常，27例（18%）儿童脑电图正常。进一步随访时患者无症状，这有助于我们确诊临床诊断。
复发性慢性腹痛是儿科医生遇到的常见问题。为了做出诊断进行了各种检查，但很少能找到病因。对于这类儿童，应考虑腹型癫痫的诊断，脑电图将确诊并采用AED治疗。
确定慢性复发性腹痛儿童中腹型癫痫的发病率，并将脑电图结果及其对经验性AED治疗的临床反应在病例组和对照组中进行关联。
印度马哈拉施特拉邦卡拉德市克里希纳医学科学大学。前瞻性分析研究。
对总共150例患有慢性复发性腹痛的儿童进行检查，以排除腹痛的常见病因并进行脑电图检查。然后所有儿童开始使用AED奥卡西平，并记录他们对治疗的反应。
150例儿童中111例（74%）脑电图显示有提示癫痫发作活动的阳性变化，其中75例（67.56%）为女性，36例（32.43%）为男性，大多数儿童年龄在9至12岁组。颞叶波放电占总异常脑电图的39例（35.13%）。所有儿童均开始使用AED，脑电图异常的儿童对治疗显示100%的反应，而27例（18%）脑电图正常的儿童也对治疗有反应。12例（8%）儿童症状无改善。
对于慢性复发性腹痛的儿童，尤其是有提示性病史的儿童，必须考虑腹型癫痫的诊断，脑电图可以使儿童避免许多不必要的检查和痛苦。
