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通过抑制分流治疗门体分流术后严重脑病

[Treatment of severe encephalopathy after porta-systemic anastomosis by suppression of the shunt].

作者信息

Marucci M M, Polastri R, Bouzari H, Mensa G, Capussotti L

机构信息

I Divisione di Chirurgia Generale, Ospedale Mauriziano Umberto I, Torino.

出版信息

Minerva Chir. 1990 Feb;45(3-4):173-6.

PMID:2356032
Abstract

Encephalopathy is the most common complication after total portal by-pass operation. 5-15% of patients have severe and intractable encephalopathy. Many medical and surgical procedures were proposed to prevent and treat this complication but none of these were effective. Two cases of patients with severe encephalopathy after side to side portal by-pass are presented. They were treated with the procedure proposed by Bismuth; it consists of a gradual suppression of the anastomosis associated with esophagogastric devascularization. In the first case we obtained the regression of encephalopathy while the second patient died portal thrombosis (probably due to this procedure) two months after surgery. Validity and efficacy of this procedure must be evaluated with a higher number of patients. This surgical technique should lead to choose the type of portal by-pass: side to side portal by-pass operation allows according to Bismuth's procedure to reestablish an hepatopetal flow.

摘要

脑病是全门静脉分流术后最常见的并发症。5%至15%的患者会出现严重且难以治疗的脑病。人们提出了许多内科和外科手术方法来预防和治疗这种并发症,但均未取得成效。本文介绍了两例端侧门静脉分流术后出现严重脑病的患者。他们接受了比斯穆特提出的手术治疗;该手术包括逐步抑制吻合口并进行食管胃去血管化。第一例患者的脑病症状得到缓解,而第二例患者在术后两个月死于门静脉血栓形成(可能是由于该手术所致)。必须通过更多患者来评估该手术的有效性和疗效。这种手术技术应有助于选择门静脉分流的类型:端侧门静脉分流术根据比斯穆特的手术方法可重建向肝血流。

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