PepsiCo R&D Nutrition, 617 W. Main Street, Barrington, IL 60010, USA.
Food Chem. 2013 Aug 15;139(1-4):426-31. doi: 10.1016/j.foodchem.2013.01.104. Epub 2013 Feb 10.
Oats are gaining increasing scientific and public interest for their purported antioxidant-associated health benefits. Most reported studies focused on specific oat extracts or particular oat components, such as β-glucans, tocols (vitamin E), or avenanthramides. Studies on whole oats with respect to antioxidant and anti-inflammatory activities are still lacking. Here the antioxidant and anti-inflammatory activities from whole oat groats of seven common varieties were evaluated. All oat varieties had very similar oxygen radical absorption capacity compared with other whole grains. In an anti-inflammatory assay, oat variety CDC Dancer inhibited tumor necrosis factor-α induced nuclear factor-kappa B activation by 27.5% at 2 mg/ml, whereas variety Deiter showed 13.7% inhibition at a comparable dose. Avenanthramide levels did not correlate with the observed antioxidant and anti-inflammatory activities. Further investigations are needed to pinpoint the specific antioxidant and anti-inflammatory compounds, and potential synergistic and/or matrix effects that may help explain the mechanisms of oat's anti-inflammatory actions.
燕麦因其据称具有抗氧化相关的健康益处而引起了越来越多的科学和公众关注。大多数报道的研究都集中在特定的燕麦提取物或特定的燕麦成分上，如β-葡聚糖、生育酚（维生素 E）或燕麦蒽酰胺。关于全燕麦的抗氧化和抗炎活性的研究仍然缺乏。本研究评估了 7 种常见品种全燕麦的抗氧化和抗炎活性。与其他全谷物相比，所有燕麦品种的氧自由基吸收能力都非常相似。在抗炎测定中，燕麦品种 CDC Dancer 在 2mg/ml 时抑制肿瘤坏死因子-α诱导的核因子-κB 激活达 27.5%，而品种 Deiter 在可比剂量下抑制 13.7%。燕麦蒽酰胺水平与观察到的抗氧化和抗炎活性没有相关性。需要进一步的研究来确定特定的抗氧化和抗炎化合物，以及可能有助于解释燕麦抗炎作用机制的潜在协同和/或基质效应。
