Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, Massachusetts 02111, USA.
Nutr Cancer. 2009;61(6):807-10. doi: 10.1080/01635580903285098.
A considerable amount of evidence indicates that tumorigenesis is associated with inflammation. Nuclear factor-kappa B (NF-kappa B), a master regulator of infection and inflammation, has been identified as a key modulator in which inflammation could develop into cancer. Dietary polyphenols have been shown to have anti-inflammatory and anticancer activity partially through inhibition of NF-kappa B activation. This review summarizes the effect of polyphenols on inflammation and cancer; avenanthramides, a unique polyphenol from oats, are especially focused.
大量证据表明，肿瘤发生与炎症有关。核因子-κB（NF-κB）是感染和炎症的主要调节剂，已被确定为炎症可能发展为癌症的关键调节剂。膳食多酚通过抑制 NF-κB 激活显示出抗炎和抗癌活性。本文综述了多酚对炎症和癌症的影响；特别关注燕麦中的一种独特多酚——燕麦蒽酰胺。
