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筛查实验室检查和心电图在儿童意外无症状摄入管理中的有限效用。

The limited utility of screening laboratory tests and electrocardiograms in the management of unintentional asymptomatic pediatric ingestions.

作者信息

Wang George Sam, Deakyne Sara, Bajaj Lalit, Yin Shan, Heard Kennon, Roosevelt Genie

机构信息

Section of Emergency Medicine, Department of Pediatrics, The University of Colorado Denver, Aurora, Colorado 80045, USA.

出版信息

J Emerg Med. 2013 Jul;45(1):34-8. doi: 10.1016/j.jemermed.2012.11.056. Epub 2013 Apr 2.

Abstract

BACKGROUND

Suspected ingestions are a common chief complaint to the emergency department although the majority of ingestions by children are insignificant.

OBJECTIVE

Assess the utility of screening laboratory tests and Electrocardiograms (ECGs) in unintentional asymptomatic pediatric poisonings.

METHODS

Retrospective chart review at a tertiary care children's hospital and a regional poison center of patients less than 12 years of age using ICD-9 codes from January 2005 through December 2008. Laboratory or ECG results requiring intervention and/or direct treatment, a non-RPC subspecialty consultation, and/or prolonged Emergency Department stay was considered changed management.

RESULTS

Five hundred ninety five suspected ingestions met our criteria. The median age was 2.6 years (IQR 1.6, 3.0 years) and 56% were male. One laboratory test or ECG was obtained in 233 patients (39%). Of 24 screening ECGs, 32 complete blood counts and 34 blood gases, none were clinically significant. Fifty-two patients received screening metabolic panels, 3 were abnormal and 2 changed management (anion gap metabolic acidosis with unsuspected salicylate ingestions). None of the 127 (21%) screening acetaminophen levels changed management. Two of sixty-five (13%) screening salicylate levels changed management. Three screening urine toxicology tests on patients with altered mental status were positive without ingestion history. No patient under the age of 12 years with normal vital signs and normal mental status had positive screening tests.

CONCLUSIONS

Screening laboratory tests and ECGs were of limited utility and rarely changed management despite being ordered in a significant number of patients. Screening tests are rarely indicated in unintentional overdoses in children who are asymptomatic.

摘要

背景

尽管大多数儿童摄入情况并无大碍,但疑似摄入是急诊科常见的主要就诊原因。

目的

评估筛查实验室检查和心电图(ECG)在无意无症状儿童中毒中的作用。

方法

对一家三级儿童医院和一个地区中毒控制中心2005年1月至2008年12月期间12岁以下患者使用ICD - 9编码进行回顾性病历审查。需要干预和/或直接治疗、非中毒控制中心专科会诊和/或延长急诊科留观时间的实验室或心电图结果被视为改变了治疗方案。

结果

595例疑似摄入符合我们的标准。中位年龄为2.6岁(四分位间距1.6,3.0岁),56%为男性。233例患者(39%)进行了一项实验室检查或心电图检查。在24份筛查心电图、32份全血细胞计数和34份血气分析中,均无临床意义。52例患者接受了筛查代谢指标检测,3例异常,2例改变了治疗方案(阴离子间隙代谢性酸中毒伴意外摄入水杨酸盐)。127例(21%)筛查对乙酰氨基酚水平均未改变治疗方案。65例(13%)筛查水杨酸盐水平中有2例改变了治疗方案。对3例精神状态改变患者进行的3次筛查尿液毒理学检测呈阳性,但无摄入史。12岁以下生命体征正常且精神状态正常的患者筛查试验均为阴性。

结论

尽管大量患者进行了筛查实验室检查和心电图检查,但它们的作用有限,很少改变治疗方案。对于无症状的儿童无意过量摄入,很少需要进行筛查试验。

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