Uthamanthil Rajesh K, Hachem Ray Y, Gagea Mihai, Reitzel Ruth A, Borne Agatha T, Tinkey Peggy T
Department of Veterinary Medicine and Surgery, Infection Control and Employee Health, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
J Am Assoc Lab Anim Sci. 2013 Mar;52(2):180-5.
Rabbits are widely used as an animal model for urologic research studies in which urinary bladder catheterization is required. However, standard manual retrograde urinary catheterization proved to be difficult to perform on anesthetized male rabbits in a research study, with frequent misplacement of the catheter into the vesicular gland. Attempts to reposition the catheter into the bladder after initial entry into the vesicular gland frequently failed and resulted in exclusion of the animal from the study. We assessed the normal anatomy of the lower urinary tract of male rabbits to determine the cause of catheterization misdirection into the vesicular gland and to develop a more reliable technique for urinary bladder catheterization. A modified 'digital (finger) pressure' catheterization technique was developed for successful urinary catheterization of male rabbits. Retrospective statistical analysis of 45 rabbits used for urinary catheterization studies showed improvement in the success rate of catheterization by using the digital pressure technique over the standard method of retrograde urinary catheter insertion. In addition, we here review the relevant gross and histologic anatomy of the urogenital tract of male rabbits.
兔子被广泛用作泌尿外科研究的动物模型，这些研究需要进行膀胱插管。然而，在一项研究中，标准的手动逆行膀胱插管在麻醉的雄性兔子身上很难进行，导管经常误插入精囊。在最初插入精囊后试图将导管重新定位到膀胱的尝试经常失败，并导致动物被排除在研究之外。我们评估了雄性兔子下尿路的正常解剖结构，以确定导管误插入精囊的原因，并开发一种更可靠的膀胱插管技术。一种改良的“指压”插管技术被开发用于成功地对雄性兔子进行导尿。对45只用于导尿研究的兔子进行回顾性统计分析表明，与标准的逆行导尿插入方法相比，使用指压技术可提高插管成功率。此外，我们在此回顾雄性兔子泌尿生殖道的相关大体和组织学解剖结构。
