Clinica Medica, Department of Medicine, General and University Hospital of Ferrara, Via Aldo Moro, 44124 Cona, Ferrara, Italy.
Heart Fail Clin. 2013 Apr;9(2):147-56, vii-viii. doi: 10.1016/j.hfc.2012.12.002.
A considerable amount of evidence has shown that the major acute cardiovascular diseases, ie, myocardial infarction, sudden cardiac death, stroke, pulmonary embolism, and rupture or dissection of aortic aneurysms do not occur randomly in time, but exhibit specific temporal patterns in their onset, according to time of day, month or season, and day of the week. This contributes to the definition of "chronorisk", where several factors, not harmful if taken alone, are capable of triggering unfavorable events when presenting all together within the same temporal window. This article reviews the actual knowledge about time of onset of takotsubo cardiomyopathy.
大量证据表明，主要的急性心血管疾病，如心肌梗死、心源性猝死、中风、肺栓塞以及主动脉瘤破裂或夹层，并非随机发生在特定时间，而是根据一天中的时间、月份或季节以及一周中的哪一天呈现出特定的时间模式。这促成了“时间风险”的定义，即当若干因素在同一时间窗口内同时出现时，即使单独存在时没有危害，也可能引发不利事件。本文综述了有关 Takotsubo 心肌病发作时间的现有知识。
