Battilani Mara, Balboni Andrea, Giunti Massimo, Prosperi Santino
Department of Veterinary Medical Sciences, Alma Mater Studiorum-University of Bologna, Via Tolara di Sopra 50-40064 Ozzano Emilia (BO), Italy.
Vet Ital. 2013 Jan-Mar;49(1):127-9.
In this study we reported a case of co-infection with canine parvovirus (CPV) type 2a and feline panleukopenia virus (FPV) in a 3-month-old male kitten, with the presence of a parvovirus variant which is a true intermediate between CPV and FPV. The report of a viral variant which contained FPV- and CPV-specific epitopes stresses the importance of the mechanism of multistep mutation in the production of new variants and in the emergence of new viruses. This type of multistep adaptation has already been documented during the emergence of CPV and on the basis of our results, it was hypothesized that CPV had presumably started a new process of readaptation in the feline host, confirming the importance of viral host switching as a mechanism for the emergence of new viruses.
在本研究中,我们报告了一例3月龄雄性小猫同时感染2a型犬细小病毒(CPV)和猫泛白细胞减少症病毒(FPV)的病例,该病例中存在一种细小病毒变体,它是CPV和FPV之间真正的中间型。一种包含FPV和CPV特异性表位的病毒变体的报告强调了多步突变机制在新变体产生和新病毒出现中的重要性。这种多步适应类型在CPV出现期间已有记录,基于我们的结果,推测CPV可能已在猫宿主中开始了一个新的重新适应过程,这证实了病毒宿主转换作为新病毒出现机制的重要性。