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社区相关耐甲氧西林金黄色葡萄球菌流行克隆株USA100；不止是一种医院病原体。

Community-associated methicillin-resistant staphylococcus aureus epidemic clone USA100; more than a nosocomial pathogen.

作者信息

Roberts Jill C

机构信息

Department of Environmental and Occupational Health, University of South Florida, College of Public Health, Tampa, FL 33612 USA.

出版信息

Springerplus. 2013 Dec;2(1):133. doi: 10.1186/2193-1801-2-133. Epub 2013 Mar 26.

DOI:10.1186/2193-1801-2-133
PMID:23565358
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3616214/
Abstract

BACKGROUND

We characterized 100 USA100 epidemic MRSA from individuals in the community with no known healthcare-associated risk factors.

FINDINGS

Molecular epidemiology demonstrated 21 pulsed-field types and six spa types. SCCmec typing demonstrated that all of the strains possess the type II cassette. The staphylococcal enterotoxin D virulence gene was also present.

CONCLUSION

Characterization of USA100 MRSA in the community illustrated the importance of nasal carriage, and the genetic diversity of the USA100 clone.

摘要

背景

我们对100株来自社区且无已知医疗相关风险因素个体的USA100流行耐甲氧西林金黄色葡萄球菌（MRSA）进行了特征分析。

研究结果

分子流行病学显示有21种脉冲场类型和6种spa类型。葡萄球菌染色体盒式 mec分型表明所有菌株均具有II型盒式结构。葡萄球菌肠毒素D毒力基因也存在。

结论

对社区中USA100 MRSA的特征分析表明了鼻腔携带的重要性以及USA100克隆的遗传多样性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/13a6/3616214/1361cf313bf9/40064_2013_189_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/13a6/3616214/1361cf313bf9/40064_2013_189_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/13a6/3616214/1361cf313bf9/40064_2013_189_Fig1_HTML.jpg

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