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Comput Biol Med. 2013 Jun;43(5):513-23. doi: 10.1016/j.compbiomed.2013.02.013. Epub 2013 Mar 20.
Retinal vessels are directly accessible to clinical observation. This has numerous potential interests for medical investigations. Using the Retinal Vessel Analyzer, a dedicated eye fundus camera enabling dynamic, video-rate recording of micrometric changes of the diameter of retinal vessels, we developed a semi-automated computer tool that extracts the heart beat rate and pulse amplitude values from the records. The extracted data enabled us to show that there is a decreasing relationship between heart beat rate and pulse amplitude of arteries and veins. Such an approach will facilitate the modeling of hemodynamic interactions in small vessels.
视网膜血管直接可供临床观察。这对医学研究有很多潜在的兴趣。我们使用视网膜血管分析仪,一种专门的眼底相机,能够动态、视频速率记录视网膜血管直径的微米级变化,开发了一种半自动的计算机工具,从记录中提取心率和脉搏幅度值。提取的数据使我们能够表明,动脉和静脉的心率和脉搏幅度呈下降关系。这种方法将有助于对小血管中血液动力学相互作用进行建模。