Ryndina N, Kravchun P, Tytova G
Kharkiv National Medical University, Kharkiv, Ukraine.
Georgian Med News. 2013 Mar(216):16-9.
The presence of concomitant anemia in many aspects defines an unfavorable course of chronic heart failure, affects patient's quality of life. Among anemic patients with chronic heart failure prevailed persons with a relative deficiency of iron. Aim of the study - to evaluate the quality of life for patients with anemia on the background of chronic heart failure, using a questionnaire FACT-An, and to analyze the existence and nature of the relations between quality of life and indicators of the iron metabolism, based on the study of transferrin saturation and ferritin. Ferritin concentration was determined by ELISA. Transferrin saturation were determined by the formula. Questionnaire FACT-An was used for assess the quality of life in anemic patients with chronic heart failure. The presence of functional iron deficiency in patients with chronic heart failure and anemic syndrome is accompanied by deterioration of parameters of quality of life mainly due to the scale of physical activity and social functioning.
在许多方面，合并贫血的存在决定了慢性心力衰竭的不良病程，影响患者的生活质量。在慢性心力衰竭贫血患者中，铁相对缺乏的人占多数。本研究的目的——使用FACT-An问卷评估慢性心力衰竭背景下贫血患者的生活质量，并基于转铁蛋白饱和度和铁蛋白的研究分析生活质量与铁代谢指标之间关系的存在情况及性质。铁蛋白浓度通过酶联免疫吸附测定法测定。转铁蛋白饱和度通过公式测定。FACT-An问卷用于评估慢性心力衰竭贫血患者的生活质量。慢性心力衰竭和贫血综合征患者存在功能性铁缺乏时，生活质量参数会恶化，主要是由于身体活动和社会功能方面。
