Department of Chemistry, The University of Burdwan, Burdwan, 713104, West Bengal, India.
Dalton Trans. 2013 May 21;42(19):6708-15. doi: 10.1039/c3dt50450f.
A naphthalene-thiophene hybrid molecule (Z)-1-((thiophen-2-ylmethylamino)methylene)naphthalen-2(1H)-one () was prepared by condensation of 2-thiophenemethylamine and 2-hydroxy-1-naphthaldehyde. According to FTIR, (1)H NMR spectrometry and single crystal X-ray analysis, exists in the cis-keto-amine tautomeric form. behaves like a molecular AND type binary logic gate with two inputs viz. Zn(2+) and OAc(-) ions whereby the fluorescence of the system turns on. The structures of and its zinc acetate complex were also optimized by DFT calculations. binds Zn(2+) in a 1 : 1 ratio with an association constant K(a) = 2.05 × 10(4) M(-1), and detects Zn(2+) as low as 3 × 10(-8) M. is useful for the detection of intracellular Zn(2+) under a fluorescence microscope.
一种萘并噻吩杂化分子（Z）-1-（（噻吩-2-基甲基氨基）亚甲基）萘-2（1H）-酮（）是通过 2-噻吩甲胺和 2-羟基-1-萘甲醛缩合制备的。根据傅里叶变换红外光谱、（1）H 核磁共振谱和单晶 X 射线分析，它以顺式-酮-胺互变异构形式存在。它的行为类似于具有两个输入（即 Zn(2+)和 OAc(-)离子）的分子 AND 型二进制逻辑门，系统的荧光打开。通过 DFT 计算还优化了和及其乙酸锌配合物的结构。以 1:1 的比例与 Zn(2+)结合，结合常数 K(a) = 2.05 × 10(4) M(-1)，并能检测到低至 3 × 10(-8) M 的 Zn(2+)。可用于荧光显微镜下检测细胞内 Zn(2+)。
