VA Pittsburgh Health Care System MIRECC and Behavioral Health Service, and Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, Pittsburgh, PA.
VA San Diego Health Care System, and Department of Psychiatry, University of California, San Diego, CA.
Am J Geriatr Psychiatry. 2014 May;22(5):437-41. doi: 10.1016/j.jagp.2013.01.039. Epub 2013 Feb 6.
Suicidal deaths in middle-aged and older individuals with schizophrenia are a public health concern. Depression and schizophrenia are major risk factors for suicide. However, it is unknown whether age moderates the relationship between depression and suicidal ideation in patients with schizophrenia and subthreshold depression.
Suicidal ideation was assessed with the InterSePT Scale for Suicidal Ideation and the Clinical Global Impression-Suicide Severity Scale in outpatients older than 39 years with schizophrenia and subthreshold depression (n = 213). Using linear regression, we examined whether depression (based on Calgary Depression Rating Scale scores), age, and "age by depressive symptoms" predicted suicidal ideation.
Depressive symptoms predicted suicidal ideation. Neither age nor "depressive symptoms by age" predicted suicidal ideation.
In this population, age does not appear to moderate the relationship between depressive symptoms and suicidal behavior. Thus, assessing depressive symptoms as a risk factor is important at all ages in this population.
中年和老年精神分裂症患者的自杀死亡是一个公共卫生关注点。抑郁和精神分裂症是自杀的主要危险因素。然而，尚不清楚年龄是否会调节精神分裂症和亚临床抑郁患者中抑郁与自杀意念之间的关系。
我们使用自杀意念量表（InterSePT Scale for Suicidal Ideation）和临床总体印象-自杀严重程度量表（Clinical Global Impression-Suicide Severity Scale）评估了 213 名年龄大于 39 岁的门诊精神分裂症和亚临床抑郁患者的自杀意念。我们使用线性回归分析，检验抑郁（基于卡尔加里抑郁评定量表分数）、年龄和“抑郁症状与年龄”是否预测自杀意念。
抑郁症状预测自杀意念。年龄和“抑郁症状与年龄的交互作用”均不能预测自杀意念。
在该人群中，年龄似乎不会调节抑郁症状与自杀行为之间的关系。因此，在该人群的所有年龄段，评估抑郁症状作为风险因素都很重要。
