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急性精神分裂症患者抑郁综合征与自杀风险之间的关系。

The relationship between depressive syndrome and suicidal risk in patients with acute schizophrenia.

作者信息

Bagaric Dario, Brecic Petrana, Ostojic Drazenka, Jukic Vlado, Goles Ana

机构信息

Dario Bagaric, Department for Integral Psychiatry, Psychiatric University Hospital Vrapce, Bolnicka cesta 32, 10000 Zagreb, Croatia,

出版信息

Croat Med J. 2013 Oct 28;54(5):436-43. doi: 10.3325/cmj.2013.54.436.

DOI:10.3325/cmj.2013.54.436
PMID:24170722
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3816561/
Abstract

AIM

To determine the relationship between scores on five factors of the Positive and Negative Syndrome Scale (PANSS) and Calgary Depression scale for Schizophrenia (CDSS) and scores on the InterSePT Scale for Suicidal Thinking (ISST) in patients with acute schizophrenia.

METHODS

Data were collected on sociodemographic and clinical characteristics of 180 drug-treated in-patients with acute schizophrenia. Their symptoms were assessed with PANSS, CDSS, and ISST and correlations between the scores were calculated. Statistically significant correlations were included in the logistic regression analysis to identify predictors of suicidal risk.

RESULTS

CDSS (P<0.001) score and negative (P<0.001), disorganized (P=0.041), emotional (P<0.001), and total score on PANSS (P<0.001) showed a significant positive correlation with ISST. Stepwise logistic regression analysis revealed that CDSS scores (odds ratio [OR] 5.18; confidence interval [CI] 1.58-16.95), and disorganized (0.90; 0.81-0.99) and emotional (1.15; 1.01-1.30) factors of PANSS were predictors of suicidal risk.

CONCLUSION

Our results suggested a considerable association between depressive syndrome as assessed by the PANSS emotional factor and CDSS score and suicidal risk in patients with acute schizophrenia.

摘要

目的

确定急性精神分裂症患者阳性与阴性症状量表（PANSS）五个因子得分、精神分裂症卡尔加里抑郁量表（CDSS）得分与自杀意念InterSePT量表（ISST）得分之间的关系。

方法

收集180例接受药物治疗的急性精神分裂症住院患者的社会人口学和临床特征数据。用PANSS、CDSS和ISST对其症状进行评估，并计算得分之间的相关性。具有统计学意义的相关性纳入逻辑回归分析以确定自杀风险的预测因素。

结果

CDSS得分（P<0.001）以及PANSS的阴性（P<0.001）、紊乱（P=0.041）、情感（P<0.001）和总分（P<0.001）与ISST呈显著正相关。逐步逻辑回归分析显示，CDSS得分（优势比[OR]5.18；置信区间[CI]1.58 - 16.95）以及PANSS的紊乱（0.90；0.81 - 0.99）和情感（1.15；1.01 - 1.30）因子是自杀风险的预测因素。

结论

我们的结果表明，PANSS情感因子和CDSS得分所评估的抑郁综合征与急性精神分裂症患者的自杀风险之间存在相当大的关联。

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