家族性心因性运动障碍。
Familial psychogenic movement disorders.
机构信息
Sobell Department of Motor Neuroscience and Movement Disorders, University College London Institute of Neurology, London, United Kingdom; Department of Neurology, University of Athens, Attiko Hospital, Athens, Greece; Neurology Clinic, Philipps University, Marburg, Germany.
出版信息
Mov Disord. 2013 Aug;28(9):1295-8. doi: 10.1002/mds.25463. Epub 2013 Apr 8.
BACKGROUND
Psychogenic (or functional) movement disorders (PMDs) are considered sporadic. Despite the growing literature describing the clinical features and the natural history of sporadic cases with PMDs, their occurrence in familial clusters is not reported.
METHODS
We identified 10 patients from 5 families affected by PMDs. In this report, we describe the clinical characteristics along with videos and long-term follow-up of these patients.
RESULTS
Clinical clues from the history and signs suggesting a functional origin of the symptoms in these patients with familial PMD were similar to those identified in sporadic cases. The phenomenology of the PMD was similar in the affected members of the same family.
CONCLUSIONS
We wish to highlight that a positive family history does not necessarily imply an organic disorder. When a positive family history for a condition is reported by a patient with PMD, examination of these further affected members may be needed and may identify further family members suffering from PMDs. A positive family history of PMDs may be an additional risk factor for developing PMDs. © 2013 Movement Disorder Society.
背景
心因性（或功能性）运动障碍（PMD）被认为是散发性的。尽管越来越多的文献描述了散发性 PMD 病例的临床特征和自然病史，但尚未报道其在家族性聚集中的发生情况。
方法
我们从 5 个受 PMD 影响的家族中确定了 10 名患者。在本报告中，我们描述了这些患者的临床特征，并附有视频和长期随访资料。
结果
家族性 PMD 患者的病史和体征中提示症状为心因性起源的临床线索与散发性病例中识别出的线索相似。同一家庭受影响成员的 PMD 表现相似。
结论
我们希望强调的是，阳性家族史并不一定意味着存在器质性疾病。当 PMD 患者报告阳性家族史时，可能需要对这些进一步受影响的成员进行检查，并可能发现更多患有 PMD 的家族成员。PMD 的阳性家族史可能是发生 PMD 的另一个危险因素。© 2013 运动障碍学会。
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