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儿童心因性运动障碍

Psychogenic movement disorders in children.

作者信息

Ferrara Joseph, Jankovic Joseph

机构信息

Parkinson's Disease Center, Department of Neurology, Baylor College of Medicine, Houston, Texas 77030, USA.

出版信息

Mov Disord. 2008 Oct 15;23(13):1875-81. doi: 10.1002/mds.22220.

Abstract

Psychogenic movement disorders (PMDs) are well characterized in adults, but childhood-onset PMDs have not been extensively studied. We reviewed the medical records of children who were diagnosed in our clinic with PMDs since 1988 and identified 54 patients with PMDs, representing 3.1% of our pediatric movement disorder population and 5.7% of all PMD cases. The mean age at symptom onset was 14.2 years (+/-2.11, range 7.6-17.7). Similar to published data in adults, two-thirds of children exhibited multiple PMD phenotypes, the most common being tremor followed by dystonia and myoclonus. Most PMDs were abrupt in onset, paroxysmal and triggered by identifiable physical or psychological trauma. As in adults, childhood PMDs were more likely to affect females, but there was no female predominance in children less than 13 years old. Although prior studies suggest that medically unexplained symptoms beginning in childhood often follow a benign course, this cohort of children experienced marked disability and morbidity related to PMDs, including prolonged school absences and unnecessary surgical procedures in more than one-fifth of patients.

摘要

精神性运动障碍(PMDs)在成人中已有充分的特征描述,但儿童期起病的PMDs尚未得到广泛研究。我们回顾了自1988年以来在我们诊所被诊断为PMDs的儿童的病历,确定了54例PMDs患者,占我们儿科运动障碍患者的3.1%,占所有PMD病例的5.7%。症状出现的平均年龄为14.2岁(±2.11,范围7.6 - 17.7)。与成人已发表的数据相似,三分之二的儿童表现出多种PMD表型,最常见的是震颤,其次是肌张力障碍和肌阵挛。大多数PMDs起病突然,呈发作性,由可识别的身体或心理创伤引发。与成人一样,儿童期PMDs更易影响女性,但13岁以下儿童中不存在女性优势。尽管先前的研究表明,儿童期开始的医学上无法解释的症状通常病程良性,但这组儿童经历了与PMDs相关的明显残疾和发病情况,包括超过五分之一的患者长期缺课和不必要的手术。

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