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(a)无症状椎体骨折:在骨质疏松症筛查的骨折患者中经常发现的具有临床相关性的实体。

The (a)-Symptomatic Vertebral Fracture: A Frequently Discovered Entity With Clinical Relevance in Fracture Patients Screened on Osteoporosis.

作者信息

de Klerk G, Hegeman J H, Bronkhorst P, van der Palen J, van der Velde D, Duis H J Ten

机构信息

Department of Surgery, Ziekenhuisgroep Twente, Almelo, The Netherlands.

出版信息

Geriatr Orthop Surg Rehabil. 2012 Jun;3(2):74-8. doi: 10.1177/2151458512449833.

Abstract

OBJECTIVE

Description of the prevalence of vertebral fractures in a fracture and osteoporosis outpatient clinic (FO-Clinic) and evaluation of the value of spinal radiographs by screening on osteoporosis.

DESIGN

Retrospective data collection, description, and analysis.

METHODS

All patients admitted to the FO-Clinic during the period of December 2005 until October 2006 were enrolled in this study. At the FO-Clinic spinal radiographs were obtained and bone mineral density (BMD) was measured by Dual energy X-ray-Absorptiometry (DXA).

RESULTS

During the study period, a total of 176 patients were screened at our FO-Clinic. In 41.5% of these patients, a vertebral fracture was diagnosed. There appeared to be an indication for anti-osteoporotic medication in 95 of the 176 patients. Of these 95 patients, 77% could be identified by spinal radiographs. Moreover, only 36% of all patients with a vertebral fracture did suffer from osteoporosis.

CONCLUSION

The prevalence of vertebral fractures in patients screened at an FO-Clinic is high and spinal radiographs can identify up to 77% of patients in which anti-osteoporotic medication should be considered. However, fracture risk is not only dependent on bone quality but also on bone density. Therefore, the preferred method of screening on osteoporosis is DXA with vertebral fracture assessment and, if necessary, spinal radiographs. If DXA is not available, spinal radiographs might be used as a first step in osteoporosis screening.

摘要

目的

描述骨折与骨质疏松门诊(FO门诊)中椎体骨折的患病率,并评估通过骨质疏松筛查的脊柱X光片的价值。

设计

回顾性数据收集、描述与分析。

方法

纳入2005年12月至2006年10月期间在FO门诊就诊的所有患者。在FO门诊拍摄脊柱X光片,并采用双能X线吸收法(DXA)测量骨密度(BMD)。

结果

在研究期间,我们的FO门诊共筛查了176例患者。其中41.5%的患者被诊断为椎体骨折。176例患者中有95例有抗骨质疏松药物治疗的指征。在这95例患者中,77%可通过脊柱X光片识别。此外,所有椎体骨折患者中只有36%患有骨质疏松症。

结论

在FO门诊筛查的患者中椎体骨折的患病率较高,脊柱X光片可识别高达77%的应考虑使用抗骨质疏松药物治疗的患者。然而,骨折风险不仅取决于骨质,还取决于骨密度。因此,骨质疏松筛查的首选方法是DXA结合椎体骨折评估,必要时进行脊柱X光片检查。如果没有DXA设备,脊柱X光片可作为骨质疏松筛查的第一步。

相似文献

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本文引用的文献

1
Bone densitometry and vertebral fracture assessment.骨密度测定和椎体骨折评估。
Curr Osteoporos Rep. 2010 Sep;8(3):123-30. doi: 10.1007/s11914-010-0018-z.
5
Long-term risk of incident vertebral fractures.椎体骨折发生的长期风险。
JAMA. 2007 Dec 19;298(23):2761-7. doi: 10.1001/jama.298.23.2761.
10
Risk of new clinical fractures within 2 years following a fracture.骨折后2年内发生新的临床骨折的风险。
Osteoporos Int. 2006;17(3):348-54. doi: 10.1007/s00198-005-2026-x. Epub 2005 Dec 24.

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